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|本期目录/Table of Contents|

犬心房功能不应期与房室结有效不应期对比研究(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2000年第5期
页码:
353-354, 357
栏目:
论著
出版日期:
2000-10-25

文章信息/Info

Title:
Comparative study on atrial functional refractory period and atrioventr icular nodal effective refractory period in the dog
作者:
赵贵锋;  杜日映;  郑强荪;  盛斌
第四军医大学唐都医院心内科, 陕西西安710038
Author(s):
ZHAO Gui-feng; 　DU Ri-ying; 　ZHENG Qiang-sun; 　SHENG Bin
Department of Cardiology,Tangdu Hospital,Fourth Military Medical University,Xi′ an 710038,Shaanxi,China
关键词:
心房; 房室结; 不应期; 电生理学; 美托洛尔; 狗
Keywords:
atrium; atriovertricular node; refractory peroid; electrophysio logy; metoprolol; dog
分类号:
R541.7
DOI:
-
文献标识码:
A
摘要:
为进一步了解房室传导的电生理特性,对8只犬在体条件下的心房功能不应 期(AFRP)和房室结有效不应期(AVNERP)进行对比研究。采用心房期前刺激法,记录静注 美托洛尔阻断心脏β受体前后不同基础周期条件下的电生理参数,绘制成房室传导曲线。分 析发现静注美托洛尔前后各个基础周期条件下,8只犬AVNERP均不能测出;相同基础周期条件 下,美托洛尔用药前后房室传导曲线有明显变化,AFRP也明显延长(P＜0.05)。结果提示不 同种 属间心肌不应期存在差异,犬AVNERP始终小于AFRP这一特点可能是其自身生理特性的功能体现。
Abstract:
In order to observe further electrophysiologic characteristic s of atrioventricular (AV) conduction,We compared atrial functional refractory pe roid (AFRP) and atrioventricular nodal effective refractory period (AVNERP) in 8 dogs. AV condution was assessed by atrial extrastimulus technique using at leas t two basic cycle lengths. The electophysiologic parameters were recorded befor e and after administering intravenous Metoprolol to block the β-receptor in th e heart, and plotted into the AV conduction curve. As a result,the AVNERP could n ot be measured in any dog. AV conduction curve showed significant changes before and after the administration of Metoprolol at equivalent basic cycle length,AFR P also showed significant prolongation. It domonstrated that the refractory peri ods of cardiac conduction are obvious difference in different species. The prope rties that AVNERP is permanently shorter than AFRP in the dog may be functional manifestation of its physiologic characteristics.

参考文献/References

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［2］ McGuire MA,RoBotin MC,Yip ASB,et al. Electrophysiologic and histologic eff ects of dissection of the connections between the atrium and posterior part of t he atrioventricular node［J］. J Am Coll Cardiol,1994,23(3):693.

［3］ 陈　新，王方正，孙瑞龙. 临床心脏电生理学和心脏起搏［M］. 北京：人民卫生出 版社，1997，364.

［4］ Holmes D,Jr. Clinical electrophysiologic assessment［A］. Robert OB,et al. eds. Cardiology:Fundamental and practice. Chicago,Yr BK Pub,1987:484.

［5］ Ho SY,Kilpatrick L,Kanai T,et al. The architecture of the atrioventric ular conduction axis in dog compared to man its significance to ablation of the atrioventricular nodal approaches［J］. J Cardiovasc Electroph ysiol,1995,6(1):26.

［6］ Childers R. The AV node:normal and abnormal physiology［J］. Prog Cardio vasc Dis,1977,19(5):361.

备注/Memo

备注/Memo:
收稿日期：1999-06-17.
更新日期/Last Update: 2000-10-25