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组织多普勒显像技术检测缺血心肌的局部舒张功能(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2001年第5期
页码:
366-368
栏目:
论著
出版日期:
2001-09-01

文章信息/Info

Title:
Non-invasive detection of regional distolic function in ischemic myocardium with tissue Doppler imaging
作者:
王文清;  刘金耀;  郭华朝;  王新宴;  宁　波;  汪　娜;  石津生;  杜　军;  刘　波
空军总医院老年病科, 北京100036
Author(s):
WANG Wen-qing ;  LIU Jin-yao;  GUO Hua-chao; WANG Xin-yan;  NING Bo; WANG Na;  SHI Jin-sheng ; DU Jun; LIU Bo
Department of Geronology, Air Force General Hospital,Beijing 100036, China
关键词:
缺血性心脏病;  左室局部舒张功能;  组织多普勒显像;  超声心动描记术
Keywords:
ischemic heart disease;  regional distolic function;  tissue Doppler imaging; echocardiography
分类号:
R541.4; R540　
DOI:
-
文献标识码:
A
摘要:
目的 评价组织多普勒显像(TDI) 技术检测缺血心肌局部舒张功能的价值。方法 应用超声心动图分别记录心肌缺血组(28 例) 和对照组(30 例) 舒张期二尖瓣血流频谱(TMF) 及左室基底部、中部和心尖部3 个水平面15 节段心肌TDI。结果 两组间左室射血分数相近(62% ±9% vs 66% ±8% , P > 0. 05)。心肌缺血组与对照组比较,TMF 舒张早期减速度时间(282±17 ms vs 201±11 ms, P < 0. 05) 和等容舒张时间(92±18 ms vs 61±10 ms, P <0. 01) 延长; E/A 比值增加(0. 67±0. 2 vs 1. 6±0. 5, P < 0. 01)。对照组TDI 示左室基底部与中部心肌舒张早期舒 张速度(Em ) 高于心尖部(P < 0. 05) , 缺血节段Em 降低, 局部早期舒张减速度时间和等容舒张时间延长。结论 TDI 可无创检测左室局部舒张功能。
Abstract:
AIM To assess the regional diastolic function of myocaardial ischemia with tissue Doppler imaging (TDI). METHODS 30 cases control subjects (Con) and 28 cases of patients with ischemic heart diseases (IHD)were enrolled. Global and reginal isovalumic relaxation time (IRT ,IRTm ) , deceletation time of early filling (DCT , DCTm ) , early distolic velocity (E, Em ) , late distolic velocity (A , Am ) , E/A and mE/mA were measured by pulsed Doppler echocardiography and TDI respectively. RESULTS There were no difference in LVEF between IHD and Con-groups ( 62% ± 9% vs 66% ± 8% , P > 0. 05).Compared with Con, DCTm and IRTm were prolonged (282±17ms vs 201±11ms, 92±18ms vs 61±10ms, P < 0. 01, respectively) in IHD-group. The Em of basal and middle level of left ventricle were higher than apical level in Con-group; The slower Em , longer IRTm and DCTm were found in ischemic segments. CONCLUSION TDI can non-invasive evaluate the regional diastolic function of ischemic myocardium. It is a valid and senssitive method for detecting of cardiac diastolic function of coronary artery disease.

参考文献/References

[1] 周晓东, 钱蕴秋, 臧益民, 等. 二维超声心动图定量检测局部左室功能的计算方法[J]. 中华物理医学杂志, 1991, 13: 19- 23.

[2] 刘金耀, 钱蕴秋, 臧益民, 左室局部收缩在冠心病诊断中的应用价值[J]. 中国心功能杂志, 1995, 7: 137- 142.

[3] 刘金耀, 钱蕴秋, 周晓东, 等, 舒张期二尖瓣血流与心肌缺血分级的关系(脉冲多普勒超声心动图的动物实验研究) [J]. 中华超声医学影像杂志, 1994, 3: 255- 257.

[4] 刘金耀, 钱蕴秋, 周晓东, 等, 舒张期二尖瓣血流与心肌缺血分级的关系(脉冲多普勒超声心动图与冠脉造影对照研究) [J]. 中华超声医学影像杂志, 1994, 3: 193- 215.

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备注/Memo

备注/Memo:
收稿日期：2001-01-05.
更新日期/Last Update: 2001-09-01