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放射性核素反义脱氧寡核苷酸治疗在PTCA 术后再狭窄中的阻抑作用(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第3期
页码:
255-257
栏目:
综述
出版日期:
2002-05-01

文章信息/Info

Title:
-
作者:
侯英萍;  邓敬兰;  乔宏庆
第四军医大学西京医院核医学科, 陕西 西安 710032
Author(s):
-
关键词:
放射性核素;  基因治疗;  血管成形术;  经腔;  经皮冠状动脉;  狭窄
Keywords:
-
分类号:
R817.5　
DOI:
-
文献标识码:
A
摘要:
作者概述了单纯反义脱氧寡核苷酸(ODNs)、单纯放射性核素和放射性核素反义ODNs 治疗在经皮腔内冠状动脉成形术后血管再狭窄中的阻抑作用其应用前景。
Abstract:
-

参考文献/References

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[4]兰燕平,崔长琮,徐仓宝,等. PTCA术后再狭窄的防治——在体局部导入反义寡核苷酸的实验研究[J].中国病理生理杂志,1998,14(7):944.

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[6] Waksman R, Rodriguez JC, Robinson KA,et al. Effect of intravascular irradiation on cell proliferation,apoptosis,and vascular remodeling after balloon overstretch injury of porcine coronary arteries[J].Circulation, 1997, 96: 1944.

[7] Waksman R, Robinson KA, Crocker IR,et al. Intracoronary low-doseβ-irradiation inhibits neointima formation after coronary artery balloon injury in the swine restenosis model[J].Circulation, 1995,92(10): 3025.

[8] Teirstein PS, Massullo V, Jani S,et al. Catheter-based radio-therapy to inhibit restenosis after coronary stenting[J].N Engl J Med, 1997,336(24): 1697.

[9] KingⅢSB, Williams DO, Chougule P,et al. Endovascularβ-radiation to reduce restenosis after coronary balloon angioplasty: Results of the beta energy restenosis trial (BERT)[J].Circulation, 1998, 97(20): 2025.

[10]Hehrlein C, Stintz M, Kinscherf R,et al. Pureβ-particle-emitting stents inhibit neointima formation in rabbits.Circulation,1996,93:641.

[11]Watanabe N,Sawai H, Endo K,et al. Labeling of phosphorothioate antisense oligonucleotides with Yttrium-90[J].Nucl Med Biol, 1999,26(2): 239.

[12]张裕民, Mather SJ, Britton KE.99Tcm标记c-myc mRNA反义寡核苷酸探针[J].中华核医学杂志, 1998, 18(3): 175.

备注/Memo

备注/Memo:
收稿日期：2000-09-15.
更新日期/Last Update: 2005-05-01