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|本期目录/Table of Contents|

eNOS 基因多态性与冠心病(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第3期
页码:
262-263
栏目:
综述
出版日期:
2002-05-01

文章信息/Info

Title:
-
作者:
徐　凯 综述;  贾国良 审校
第四军医大学西京医院心内科, 陕西 西安 710032
Author(s):
-
关键词:
一氧化氮合酶;  内皮型;  冠状动脉疾病
Keywords:
-
分类号:
Q559; R541.4
DOI:
-
文献标识码:
A
摘要:
本文在回顾了内皮型一氧化氮合成酶的基因多态性的基础上, 着重综述了Glu298→A sp 基因突变与冠心病发生的关联性。
Abstract:
-

参考文献/References

[1] 丁 钢,左春梅,黄永麟.一氧化氮在心肌缺血再灌注时对心肌功能的影响[J].心功能杂志,1999,11(3):194.

[2] Hingorani AD,Chia FL,Jenny F,et al. A common variant of the endothelial nitric oxide synthase (Glu298→Asp) is a major risk factor for coronary artery disease in the UK[J].Circulation,1999,100(14):1515.

[3] Hibi K,Ishigami T,Tamura K,et al. Endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction [J]. Hypertension,1998,32(3):521.

[4] Ichihara S,Yamada Y,Fujimura T,et al. Association of a polymorphism of the endothelial constitutive nitric oxide synthase gene with myocardial infarction in the Japanese population[J].Am J Caridol,1998,81(1):83.

[5] Shimasaki Y,Yasue H,Yoshimura M,et al. Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myocardial infarction[J].J Am Coll Cardiol, 1998, 31(7):1506.

[6] Hooper WC,Cathy L,Harland A,et al. The relationship between polymorphisms in the endothelial cell nitric oxide synthase gene and the platelet GPⅢa gene with myocardial infarction and venous thromboembolism in African Americans[J].Chest,1999,116(4):880.

[7] Wang XL,Sim AS,Badenhop RF,et al. A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene [J].Nat Med,1996,2(1):41.

[8] Philip I,Plantefeve G,Vuillaumier BS,et al. G894T polymorphism in the endothelial nitric oxide synthase gene is associated with an enhanced vascular responsiveness to henylephrine[J].Circulation,1999,99(24):3096.

[9] Liao YL,Keijiro S,Jiafu O,et al. A missense mutation of the nitric oxide synthase (eNOS) gne (Glu298Asp) in five patients with coronary artery disease[J]. Angiology, 1999, 50(8): 671.

备注/Memo

备注/Memo:
收稿日期：2000-11-13.
更新日期/Last Update: 2005-05-01