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冠心病患者平板运动试验中QT离散度变异的临床意义(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第5期
页码:
408-410
栏目:
临床研究
出版日期:
2002-09-01

文章信息/Info

Title:
The significance of QT dispersion during exercise treadmill test in patients with coronary heart disease
作者:
赵瑞平;  宋志军;  孙 凯
包头中心医院心内科, 内蒙古包头 014060
Author(s):
ZHAO Rui-ping;  SONG Zhi-jun;  SUN Kai
Department of Cardiology of Central Hospital of Baotou,Nei Monggol,014040,China
关键词:
平板运动试验; 冠状动脉造影; QT离散度
Keywords:
exercise treadmill test;  QT dispersion; coronary artery disease
分类号:
R540.47
DOI:
-
文献标识码:
A
摘要:
目的 探讨平板运动试验中冠心病患者QT离散度(QTd)变化的意义。方法 经冠状动脉造影术证实的14例冠心病患者与16例冠脉造影正常者平板运动试验前、中、后体表心电图QTd变化。结果 运动前、中、后冠心病组QTd分别为43±16,70±18及48±11 ms,而冠状动脉正常组分别为29±4,29±6及27±8 ms。两组均P<0.01;冠心病组QTd运动中与运动前后相比均P<0.01,而冠脉正常者差异并无显著性;以运动中QTd≥60 ms判为异常,诊断冠心病的敏感性为86%,特异性为92%。结论 在平板运动试验中冠心病患者QTd显著增大,它是运动试验中诊断冠心病的特异指标。
Abstract:
AIM To investigate the clinical significance of QT dispersion (QTd) during exercise treadmill test in patients with coronary artery disease.METHODS QTd of 12-lead surface ECG was measured when ST segments depression was more than 1 mm or typical angina occurred or submaximal heart rate was achieved,and after exercise treadmill test 14 patients with coronary artery disease and 16 patients with normal coronary arteries was identified by coronary angiography. RESULTS The QTd were significantly increased in patients with coronary artery disease before,during and after exercise (43±16,70±18,48±11 ms respectively),compared with those in patients with normal coronary arteries (29±±4,29±6,27±8 ms respectively),allP<0.01,in patients with coronary artery disease,QTd were significantly increased during exercise compared with those before and after exercise(P<0.01). There were no significant changes in QTd in patients with normal coronary arteries before,during and after exercise. Stress QTd of≥60 ms, the sensitivity is 86% and specificity is 92% for the diagnosis of coronary artery disease.CONCLUSION QTd is significantly increased in patients with coronary artery disease during exercise test,QTd during exercise treadmill test could be used as a specific index for the diagnosis of coronary heart disease.

参考文献/References

[1] 吴学忠,刘文娴,吕树铮,等.平板运动试验和潘生丁负荷试验对冠心病的诊断意义[J].中华心血管病杂志,1996,24:293-295.

[2] Van de loo A,Arends W.Hohnlose SH. Variability of QT dispersion measurement in the surface electrocardiogram in patients with acute myocardial infarction and in normal subjects [J].Am J Cardiol,1994,74:1113-1118.

[3] Lange RA. Cigarro RG. Well PJ,et al. Influnce of anterograde flow in the infarct artery on the incidence of late potentials after acute myocardial infarction[J].Am J Cardiol,1990,65(6):554.

[4] Zareba W,Moss AJ,Le cessie S. Dispersion of ventricular replorization and arrhythmic cardiac death in coronary artery disease[J].Am J Cardiol,1994,74:550-553.

备注/Memo

备注/Memo:
收稿日期：2001-06-04.
更新日期/Last Update: 2002-09-01