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氧化型高密度脂蛋白与动脉粥样硬化(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第5期
页码:
423-425
栏目:
综述与讲座
出版日期:
2002-09-01

文章信息/Info

Title:
-
作者:
李 莹 综述;  曾 智 审校
华西医科大学附属一院心血管内科, 四川成都 610041
Author(s):
-
关键词:
脂蛋白; 高密度; 氧化修饰; 动脉粥样硬化
Keywords:
-
分类号:
R543.5
DOI:
-
文献标识码:
A
摘要:
近年,越来越多的研究结果表明,高密度脂蛋白被氧化修饰是导致动脉粥样硬化(AS)的重要原因。被修饰后的氧化型高密度脂蛋白不仅可以导致内皮细胞代谢和功能的紊乱,还通过影响胆固醇逆转运、炎症反应、基因表达和细胞增殖以及低密度脂蛋白的代谢,促进AS的发生和发展。
Abstract:
-

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备注/Memo

备注/Memo:
收稿日期：2001-11-12.
更新日期/Last Update: 2002-09-01