我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

C-反应蛋白与冠状动脉病变的相关性及其临床意义(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2002年第6期
页码:
485-487
栏目:
临床研究
出版日期:
2002-11-01

文章信息/Info

Title:
The correlation of C-reactive protein with the coronary angiographic findings
作者:
王兴祥;  周利龙;  冯义柏;  曹林生;  曾秋棠;  程龙献
华中科技大学同济医学院附属协和医院心内科, 湖北武汉 430022
Author(s):
WANG Xing-xiang; ZHOU Li-long; FENG Yi-bai; CAO Lin-sheng; ZENG Qiu-tang; CHENG Long-xian
Department of Cardiology,Union Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technolog,Wuhan,Hubei 430022, China
关键词:
C-反应蛋白; 冠状动脉造影术; 冠状动脉粥样硬化
Keywords:
C-reactive protein; coronary angiography; coronary atherosclerosis
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 探讨血浆C-反应蛋白(CRP)与冠脉病变的稳定性、程度及范围的关系。方法 根据冠状动脉造影结果和临床表现,将135例冠心病患者分组比较他们的血浆CRP水平。结果 ①不稳定型心绞痛患者血浆CRP水平高于稳定型心绞痛患者(15.0±3.4vs5.8±0.8 mg/L,P<0.01);②冠脉堵塞组患者的血浆CRP较狭窄组患者高(18.2±3.1vs9.3±1.9 mg/L,P<0.01);③多支病变组患者的血浆CRP明显高于单支病变组患者(15.0±2.7vs6.8±0.8 mg/L,P<0.01)。结论血浆CRP水平与冠状动脉病变相关,对判断冠脉病变稳定性、程度及范围具有一定价值。
Abstract:
AIM This study examined the correlation of C-Reactive Protein(CRP) to the stability, aera and extent of coronary artery culprit lesion.METHODS 135 patients undergoing coronary angiography were included in the study. Samples for CRP were obtained at admission and measured with enzyme immunoassay.RESULTS ①The concentrations of CRP in the patients with unstable angina were higher than those in the patients with stable angina (15.0±3.4vs5.8±0.8 mg/L,P<0.01);②A clear relationship between CRP and the aera and extent of culprit lesion in coronary artery was found(18.2±3.1vs9.3±1.9 mg/L &15.0±2.7vs6.8±0.8 mg/L,P<0.01).CONCLUSION Elevated CRP may predisposes to the destabilization,area and extent of culprit lesion in coronary artery.

参考文献/References

[1] Haverkate F,Thompson SG,Pyke SDM,et al. Production of C-reactive protein and risk of coronary events in stable and unstable angina[J].Lancet,1997,349:462-466.

[2] Ross R. Atherosclerosis—an inflammatory disease[J].N Engl J Med,1999,340:115-126.

[3] Liuzzo G,Biasucci M,Gillamore JR,et al. The prognostic value of C-reaactive protein and serum amyloid A protein in severe unstable angina[J].N Engl J Med,1994,331:417-424.

[4] Berk BC,Weintraub WS,Alexander RW. Elevation of C-reactive protein in“active”coronary artery disease[J].Am J Cardiol,1990,65:874-879.

[5] Biasucci LM,Vitelli A,Liuzzo G,et al. Elevated levels of inter-leukin-6 in unstable angina[J].Circulation,1996,94,874-879.

[6] Moreno PR,Falk E,PaLacios If,et al. Macrophage infltration in acute coronary syndromes:implications for plaque rupture[J].Circulation,1994,90:2844-2850

备注/Memo

备注/Memo:
收稿日期：2001-08-06.
更新日期/Last Update: 2002-11-01