我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

极化液治疗急性心肌梗死的临床应用研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2003年第1期
页码:
81-83
栏目:
综述
出版日期:
2003-01-01

文章信息/Info

Title:
-
作者:
范忠才 综述; 曾智 审校
四川大学华西医院心内科,四川 成都 610041
Author(s):
-
关键词:
胰岛素; 葡萄糖; 心肌梗塞; 急性
Keywords:
-
分类号:
R542.2
DOI:
-
文献标识码:
A
摘要:
早期的极化液(GIK)治疗急性心肌梗死(AMI)的临床试验没有得出确切的结论。近年来的几组前瞻性、随机临床对照试验显示GIK可明显降低AMI患者的病死率。实验研究证明GIK对缺血及再灌注心肌具有明显的保护作用。
Abstract:
-

参考文献/References

[1] Apstein CS. Increased glycolytic substrate protection improves ischemic cardiac dysfunction and reduces injury [J].Am Heart J, 2000, 139(2 pt 3):S107-S114.

[2] Weiss JN, Lamp ST. Glycolysis preferentially inhibits ATP sensitive K+ channels in isolated guinea pig cardiacmyocytes [J] . Science, 1987, 238(4823):67-69.

[3] Eberli FR, Weinberg EO, Grice WN, et al. Protective effects of increased glycolytic substrate against systolic and diastolic dysfuction and increased coronary resistance from prolonged global under perfusion and reperfusion in isolated rabbit hearts perfused with erythrocyte suspensions [J] . Circ Res, 1991, 68(2):466-481.

[4] Fath-Ordoubadi F, Beatt KJ. Glucose-insulin-potassium therapy for treatment of acute myocardial infarction: an overview of randomized placedbo-controlled trials [J] . Circulatoin, 1997, 96(4):1152-1156.

[5] Lazar HL, Philippides G, Fitzgerald C, et al. Glucose-insulin potassium solutions enhance recovery after urgent coronary artery bypass grafting [J] . J Thorac Cardiovasc Surg, 1997, 113(2):354362.

[6] Vanoverschelde JLJ, Janier MF, Bakke JE, et al. Rate of glycolysis during ischemia determines extent of ischemic injury andfunctional recovery after reperfusion [J] . Am J Physiol, 1994, 267(5 pt 2):H1785-H1794.

[7] Diaz R, Paolasso EA, Piegas LS, et al. Onbehalf of the ECLA(Estudios Cardiologicos Latin america) collaborative group. Metabolic modulation of acute myocardial infarction:the ECLA glucose-insulin-potassium pilot trial [J] . Circulation, 1998, 98(21):2227-2234.

[8] Fontbonne A, Charles MA, Thibult N, etal. Hyperinsulinaema a predictor of coronary heart disease mortality in a healthy population: the paris prospective study, 15 yearfollow up [J] . Diabetologia, 1991, 34(2):356-365.

[9] King GL, Goodman AD, Buzney S, et al. Receptor and growth promoting effects of insulin and insulin-like growth factors on cells from bovine retinal capillaries and aorta [J] . J Clin Invest, 1985,75(3):1028-1035.

[10] Milavetz JJ, Giebel DW, Christian TF, et al. Time to therapy and salvage in myocardial infarction [J]. J Am Coll Cardiol, 1998, 31(4):1246-1251.

[11] Chareonthaitawee P, Christian TF, O'Connor MK, et al. Noninvasive prediction of residual blood flow within the risk area during acute myocardial infarction: a multicenter validation study of patients under going direct coronary angioplasty [J] . Am Heart J, 1997, 134(4):639-646.

[12] Rackley CE, Russell RO, Rogers WJ, et al. Clinical experience with glucose-insulin-potassium therapy in acute myocardiol infarction [J] . Am Heart J, 1981, 102(6 pt 1):1038-1049.

[13] Arsenian M, New PS, Cafasso CM. Safety, tolerability and efficacy of a glucose-insulin-potassium-magnesium-carnitine solution in acute myocardiol infarction [J] . Am J Cardiol, 1996, 78(4):476-479.

[14] Apstein CS. Glucose-insulin-potassium for acute myocardiol infarction. Remarkable results from a new prospective,randomized trial [J] . Circulations, 1998, 98(21):2223-2226.

[15] Lazar HL, Chipkin S, Philippides G, et al. Glucose-insulin potassium solutions improve outeomes in diabetics who have coronary artery operations [J] . Ann Thorac Surg, 2000, 70(1):145-150.

[16] Apstein CS, Taegtmeyer H. Glucose-insulin potassium in acute myocardial infarction [J] . Circulation, 1997, 96(4):1074-1077.

[17] Ceremuzynski L, Budaj A, Gzepiel A, et al. ForPol-GIK trial investigators. Low-doseglucose-insulin-potassium is ineffective in acute myocardial infarction. Results of randomized multicenter Pol-GIK trial [J] . Cardiovasc Drugs Ther, 1999, 13(1):191-200.

[18] Weisinger JR, Bellorin-Font E. Magnesium and phosphorus [J].Lancet, 1998, 352(9125):391-396.

备注/Memo

备注/Memo:
收稿日期：2001-10-22.
更新日期/Last Update: 2003-01-01