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血清总胆红素与冠状动脉狭窄的相关性(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2003年第5期
页码:
432-433,436
栏目:
临床研究
出版日期:
2003-09-01

文章信息/Info

Title:
Association of total serum bilirubin concentration with coronary atherogenesis of coronary artery diseas
作者:
孙全格1; 童文玲1; 武文1; 郑强荪2; 柳荫2; 薛玉生2
1.武警山东总队医院内一科,山东 济南 250014;2.第四军医大学唐都医院心内科 陕西 西安 710038
Author(s):
SUN Quan-gei1;  TONG Wen-ling1;  WU Wen1;  ZHENG Qiang-sun2; LIU Yin2;  XUE Yu-sheng1
1.Department of Cardiology, Shandong Provincial Corps Hospital, Chinese People's Armed Police Forees, Jinan, Shandong 250101, China; 2.Department of Cardiology, Tangdu Hospital, Fourth Military Medical University, Xi'an Shanxi, 710038, China
关键词:
血清总胆红素; 冠状动脉疾病; 选择性冠状动脉造影术; 冠状动脉狭窄
Keywords:
serum total bilirubin;  coronary artery disease;  selective coronary angiography;  coronary atherogenesis
分类号:
R541.1
DOI:
-
文献标识码:
A
摘要:
目的:探讨血清总胆红素水平与冠状动脉狭窄程度的关系。方法:符合条件的冠状动脉造影患者146例,根据狭窄程度分成3组。正常组:60例,血管狭窄程度<10%。轻度狭窄组:16例,狭窄程度10%～49%。重度狭窄组:70例,至少一支血管狭窄>50%。采空腹肘静脉血测定血清总胆红素水平并进行比较。结果:正常组血清总胆红素显著高于轻度狭窄组及重度狭窄组(P<0.05),轻度狭窄组与重度狭窄组之间血清总胆红素水平差异无显著性。重度狭窄组中单支病变与两支病变、单支病变与三支病变的总胆红素水平有高度显著差异(P<0.01)。血清总胆红素水平越低者,冠状动脉狭窄程度越重。结论:血清总胆红素水平与冠状动脉狭窄程度呈负相关。
Abstract:
AIM: To explore the association of low serum total bilirubin within creased risk of atherogenesis. METHODS: 146 patients who had been done selective coronary angiography were divided into 3 groups according to the coronary atherogenesis. (A)normal, all vessels stenosis 0～10%,n=60.(B)light coronary atherogenesis, at least one vessel stenosis 10%～49%,n=16. (C)Severe coronary at berogenesis, at least one vessel stenosis> 50%, n=70.Their serum total bilirubin concentrations were measured and compared. RESULTS: The serum bilirubin concentration of group A was significant higher than that of group B and group C(P<0.05). Whereas there were no statistical difference between group B and group C. There were significant statistical difference betweenⅠandⅡ,Ⅰand Ⅲ in group C(P<0.01).Chisquaretest revealed a significant inverse association between serum total bilirubin concentration and the morbidity of CAD. Those with lower bilirubin levels showed a more severe of coronary atherogenesis. CONCLUSION: The serum total bilirubin had negative correlation with coronary atherogenesis.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2002-05-27.
更新日期/Last Update: 2003-09-01