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|本期目录/Table of Contents|

经皮腔内冠状动脉成形术对急性心肌梗死患者左心室功能的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2003年第5期
页码:
449-451
栏目:
介入治疗
出版日期:
2003-09-01

文章信息/Info

Title:
Contribution of PTCA to the improvement of left ventricular function after myocardial infarction
作者:
李爱国; 尤乃祯; 傅绪杰; 刘建平; 李晓燕; 刘现亮; 魏敏; 刘科卫
济南军区总医院心血管内科, 山东 济南 250031
Author(s):
LI Ai-guo;  YOU Nai-zhen;  FU Xu-jie;  LIU Jian-ping;  LI Xiao-yan;  LIU Xian-liang;  WEI Min;  LIU Ke-wei
Department of Cardiology, Jinan Military General Hospital, Jinan, Shandong 250031, China
关键词:
心肌梗塞; 血管成形术; 心室功能; 左
Keywords:
myocardial infarction;  angioplasty;  ventricular function;  left
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的:评价延迟的经皮腔内冠状动脉成形术(PTCA)对急性心肌梗死(AMI)患者左心室功能恢复的影响。方法: 63 例初次Q 波型AMI 患者, 于发病2～3 周内分别进行PTCA治疗。全部病例梗死相关血管均为完全或次全闭塞病变。经过左心室造影计算左室射血分数(LVEF)。梗死区室壁运动百分率及Cortina 室壁运动不良积分。PTCA 术6 个月后所有患者重复进行左心室造影及重复以上指标的测量。结果: 在PTCA 术6 个月后, 本组病例表现出左室局部及整体收缩功能明显改善, PTCA 前后LVEF (58±11)% vs (51±10)% , P<0.01; 梗死区室壁运动百分率(14±6)% vs (12±6)% , P<0.05。Cortina 室壁运动不良积分下降(8±4) 分vs (10±4) 分, P<0.01。结论:Q 波型AMI 患者接受延迟的PTCA 再血管化治疗能改善左心室功能。
Abstract:
AIM: To assess the effect of late revascularization by primary perculaneous transluminal coronary angioplasty (PTCA) on left ventricular function of patients with acute myocardial infarction (AMI). METHODS: PTCA were performed in 63 AMI patients with in itial Q-wave with in 2～3 weeks after myocardial infarction. The infarct-related artery was totally or sub totally occluded in each patient. Left ventricular ejection fraction (LVEF), percent regional wall motion of infarcted wall and cortina dysfunction score were measured by left ventriculography. The above measurements and left ventriculography were performed again 6 months after PTCA. RESULTS: 6 months after PTCA, the patients showd a significant improvement in LVEF (58±11)% vs (51±10)%, P<0.01, and percent regional wall motion of infarcted wall (14±6)% vs(12±6)%, P<0.05. The cortina dysfunction score was reduced signtificantly (8±4) vs (10±4), (P<0.01). CONCLUSION: In initial Q-wave myocardial infarction even with late reperfusion, PTCA had beneficial effects on left ventricular function.

参考文献/References

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[2] Lorelei L, Grines J, Timothy H, et al. Arandomized trial of transfer for primary angioplasty versus on-site thrombolysis in patients with high-risk myocardial infarction [J]. J Am Coll Cardiol, 2002, 5:1713-1719.

[3] Sadanandan S, Hochman JS. Early reperfusion, late reperfusion, and open artery hypothesis: An overview [J] . Prog Cardiovasc Disease, 2000, 6:397-404.

[4] Halvo rsen S, Muller C, Bendz B, et al. Left ventricular function and infarct size 20 months after primary angioplasty for acute myocardial infarction [J] . Scand Cardiovasc J , 2001, 35(6):379-84.

[5] 郑晓明, 贾国良. 超声心动图评价PTCA手术前后左心功能变化 [J] . 心脏杂志, 2002, 14(2):142-144.

[6] Bogaert J, Maes A, Van de werf F, et al. Functional recovery of subepicardial myocardial tissue in transmural myocardial infarction after successful reperfusion [J] . Circulation, 1999, 99:36-43.

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备注/Memo

备注/Memo:
收稿日期：2002-05-02.
更新日期/Last Update: 2003-09-01