我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

心脉宁胶囊对血液流变学的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2004年第3期
页码:
224-225
栏目:
实验研究
出版日期:
2004-05-01

文章信息/Info

Title:
Effect of xinmaining capsule on hemorrheology
作者:
石玉; 黄茶; 王向
第四军医大学西京医院药剂科，陕西 西安 710032
Author(s):
SHI Yu; HUANG Qin; WANG Xiang-rong
Department of Pharmacy，Xijing Hospital，Fourth Military Medical University，Xi'an,Shaanxi 710032，China
关键词:
心脉宁胶囊; 家兔; 大鼠; 血液流变学
Keywords:
xinmaining capsule; rabbit; rat; hemorrheology
分类号:
R285. 5;R541.4
DOI:
-
文献标识码:
A
摘要:
目的:探讨心脉宁胶囊对血小板聚集、血液猫度和血栓形成的影响。方法:家兔7只，颈动脉放血，观察不同浓度的心脉宁及给药后不同时间点血小板聚集和聚集抑制百分率;SD大鼠24只，用不同浓度的心脉宁灌胃，于颈动脉放血测量血液猫度;SD大鼠30只，用不同浓度的心脉宁灌胃，于颈内静脉置丝线后对丝线上形成的血栓称重。结果:不同浓度的心脉宁对家兔血小板聚集均有抑制作用。随心脉宁浓度的增加，对血小板聚集抑制作用也随之增加(P<0.05 ,P<0.01 )。每天喂养心脉宁(6g /kg)可使大鼠各项血液钻度指标明显降低(P<0.05 或P<0.01 )。不同浓度的心脉宁喂养组均与对照组血栓湿重有显著差异(P<0.0 1),结论:心脉宁可使血液钻度降低，对血小板聚集和血栓形成具有抑制作用。
Abstract:
AIM:To investigate the effect of xinmaining capsule on hemorrheological parameters，including platelet congregation，blood conglutination and thrombosis. METHODS:The platelet congregation percentage and platelet congregation restraining percentage in carotid blood were detected in 7 rabbits by using various concentration of xinmaining and at various time points after xinmaining administration. After gastric lavages with different concentrations of xinmaining, the blood conglutination in carotid blood was detected and thrombus weights formed on the silk threads in jugular veins were measured in 24 and 30 SD rats respectively. RESULTS:It was found that various concentrations of xinmaining restrained platelet congregation of rabbit. Restraining effect on platelet congregation increased when xinmaining concentration was increased (P<0. 05 and P<0. 01). Blood conglutination parameters markedly reduced when xinmaining(6 g/kg) was fed every day(P<0. 05 and P<0. 01).There was significant difference between the groups fed with different concentrations of xinmaining and the control group(P<0. 01).CONCLUSION: Xinmaining can reduce blood conglutination and restrain platelet congregation and thrombosis.

参考文献/References

[1]唐荔，李迎春，苏志家，等.德通心脉宁防治大鼠心肌缺血和心律失常[J].第四军医大学学报，1998,19(4):426-427.

[2]李楚杰.临床病理生理学(下册)[M].广州:广东科学技术出版社，1990.231.

[3]冯晓滨，减益民，吴作舟，等.犬冠脉前降支块血区早期局部血液温度变化[J].第四军医大学学报，1989,10(6),402-4 4.

[4]习周小明，陆再炎，江道义.丹参防止实脸性再狭窄及其机制的初步研究[J].中国中西医结合杂志，1996,16(5),480-482.

[5]康建华，张跃义，赵连友.比较复方丹参滴丸与丹参片治疗冠心病心绞痛的疗效[J].心脏杂志，2002,14(4),323-324.

[6]鲍臻，互天，王宗仁，等.蔑丹通脉片对急性心肌缺血犬血液流变学及生化指标的形响[J].心脏杂志,2001,13(2),125-127 .

[7]侯云生，何国祥，何振山，等.黄芪对急性心肌梗死后左室重构的治疗作用[J].心脏杂志,2000,12(4).270-2 72.

备注/Memo

备注/Memo:
收稿日期：2003-1-10
更新日期/Last Update: 2004-05-01