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经皮冠状动脉介入治疗对心肌梗死患者心功能的影响(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2004年第4期
页码:
329-331
栏目:
临床研究
出版日期:
2004-07-01

文章信息/Info

Title:
Effect of percutaneous coronary intervention on cardiac contractive function of patients with myocardial infarction
作者:
杨丽霞; 齐峰; 王先梅; 石燕昆; 王燕; 郭传明; 李丽俐; 任丽
成都军区昆明总医院心内科，云南 昆明 650032
Author(s):
YANG Li-xia; QI Feng;  WANG Xian-mei; SHI Yan-kun; WANG Yan; GUO Chuan-ming;  LI Li-li; REN Li
Department of Cardiology，Kunming General Hospital of Chengdu Military Area，Kun-ming，Yunnan 650032，China
关键词:
心肌梗塞; 经皮冠状动脉介入术; 心功能不全
Keywords:
myocardial infarction; percutaneous coronary intervention; cardiac dysfunction
分类号:
R542.22
DOI:
-
文献标识码:
A
摘要:
目的:评价心肌梗死并左心功能不全患者经皮冠状动脉介人(PCI)治疗对左心收缩功能和左心室重构的影响。方法:急性心肌梗死(AMI)患者30例，陈旧性心肌梗死(OMI)22 例，经PTCA、支架术治疗，术后随访3个月，超声心动图测定左室舒张末内径(LVEd)、左心房内径(LAd)、左室舒张末容积(LVEDV)、左室收缩末容积(LVESV)、左室射血分数(LVEF)和左室短轴缩短率(LVFS)，比较治疗前后各参数的变化。结果:PCI治疗后LVEd, LAd, LVEDV, LVESV显著减少(P<0.01),LVEF和LVFS显著增高(P<0.01),尤以AMI组明显，并且冠状动脉血运重建的时间越早，心功能恢复越好。结论:心肌梗死并左心功能不全患者尽早PCI治疗可明显改普左心室收缩功能，可部份阻抑左心室重构。
Abstract:
AIM:To assess the effect of percutaneous coronary intervention (PCI) on the cardiac contractive function and remodeling of the left ventricle of myocardial infarction patients over a 3-month period. METHODS:30 cases with acute myocardial infarction (AMI) and 22 old myocardial infarction (OMI) patients were treated by percutaneous transluminal coronary angioplasty (PTCA) and stent. Three-month follow-up was conducted after PCI. The left ventricular end diastolic diameter (LVEDd)，left atrial diameter (LAd)，left ventricular end diastolic volume (LVEDV)，left ventricular end systolic volume (LVESV)，left ventricular ejection fraction (LVEF) and the left ventricular fractional shortening (LVFS) indexes were measured by Doppler echocardiography and the parameters before and after PCI were compared. RESULS:The LVED, LAD, LVEDV，LVESV indexes were significantly reduced (P<0. 01) in after PCI than in before PC1. LVEF and LVFS indexes were increased apparently (P<0. 01)，especially in the AMI group. The earlier the revascularization of coronary artery，the better the cardiac function recovers. CONCLUSION:The AMI patients with left ventricular dysfunction should be treated by PCI as soon as possible，which can improve the left ventricular contractive function apparently and partly impede the remodeling of the left ventricle.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2004-4-27
更新日期/Last Update: 2004-07-01