小剂量倍他乐克治疗充血性心力衰竭对血浆脑钠尿肽水平的影响(PDF)
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2005年第2期
- 页码:
- 140-141/144
- 栏目:
- 临床研究
- 出版日期:
- 2005-03-05
文章信息/Info
- Title:
- Effect of low dose Betaloc on plasma brain natriuretic peptide level in patients with congestive heart failure
- Author(s):
- SUN Jing; QIAN Anbin
- Department of Medicine， Ningbo First Hospital,Ningbo, Zhejiang 315010， China
- Keywords:
- brain natriuretic peptide ; betaloc ; heart failure; congestive
- 分类号:
- R541.61
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 目的 观察小剂量倍他乐克治疗充血性心力衰竭（CHF）后,患者血浆脑钠尿肽(BNP)水平的改变。方法 选择心功能Ⅲ～Ⅳ级心衰患者31例,在常规抗心衰基础上加用小剂量倍他乐克,观察治疗前后血浆BNP水平的变化。结果 心率明显减慢, 心胸比和血压均较治疗前降低, 左室舒张末期内径(ＬＶＤｄ)缩短,左室射血分数(ＬＶＥＦ)则较治疗前提高, BNP值显著降低，总有效率达81%。结论 小剂量倍他乐克治疗CHF可使BNP值显著下降, 动态监测患者血浆BNP水平有助于了解CHF治疗效果及预后。
- Abstract:
- AIM To observe plasma brain natriuretic peptide level of patients with congestive heart failure (CHF) treated with low dose Betaloc. METHODS We chose 31 heart failure patients with Ⅲ～Ⅳ New York Heart Association (NYHA)functional classification,and used low dose Betaloc on the basis of traditional treatment,then observed the change in plasma brain natriuretic peptide level during the treatment. RESULTS After the treatment,patients' heart rate, blood pressure， cardiothoracic ratio and ＬＶＤｄ all declined,but ＬＶＥＦ increased. The value of BNP declined obviously, and the total effective rate was 81%.CONCLUSION The value of BNP declined obviously after the use of the Betaloc, which may help to detrmine the therapeutic effect and prognosis for CHF.
参考文献/References
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备注/Memo
- 备注/Memo:
- 收稿日期：2004-06-28.
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