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雌激素在预防血管成形术后再狭窄中的应用(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2005年第4期
页码:
398-400
栏目:
综述
出版日期:
2005-09-05

文章信息/Info

Title:
-
作者:
梁明; 韩雅玲
沈阳军区总医院全军心血管病研究所心内科，辽宁 沈阳 110016
Author(s):
-
关键词:
雌激素; 内膜增生; 再狭窄
Keywords:
-
分类号:
R543.3
DOI:
-
文献标识码:
A
摘要:
血管成形术后再狭窄是当前心血管领域的研究热点，雌激素可以促进损伤血管局部的内皮化，调节血中及损伤血管局部组织纤溶酶原激活物及其抑制剂含量，抑制球囊损伤血管局部的炎症反应、平滑肌细胞的增殖和血管壁负性重构。动物实验研究及临床研究初步证实雌激素能够预防血管成形术后再狭窄,具有良好的应用前景。
Abstract:
-

参考文献/References

［1］Gerschlick AH, Baron J. Dealing with instent restenosis［J］. Heart, 1998, 79: 319-323.

［2］Bhatia V, Bhatia R, Dhindsa S. Drugeluting intracoronary stents: have we got the magic bullet［J］. J Postgrad Med, 2003, 49(3): 291- 296.

［3］Strehlow K,Werner N, Berweiler J，et al. Estrogen increases bone marrowderived endothelial progenitor cell production and diminishes neointima formation［J］. Circulation, 2003, 107: 3059-3065.

［4］Brouchet L, Krust A, Dupont S, et al. Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptoralpha but not estrogen receptorbeta［J］. Circulation, 2001,103:423-428.

［5］Krasinski K, Spyridopoulos I, Asahara T, et al. Estradiol accelerates functional endothelial recovery after arterial injury［J］. Circulation, 1997, 95: 1768-1772.

［6］Stirone C, Chu Y, Sunday L, et al. 17 Betaestradiol increases endothelial nitric oxide synthase mRNA copy number in cerebral blood vessels: Quantification by realtime polymerase chain reaction［J］. Eur J Pharmacol, 2003, 478(1):35-38.

［7］Hayashi T, Yamada K, Esaki T, et al. Estrogen increases endothelial nitric oxide by a receptormediated system［J］. Biochem Biophys Res Commun, 1995, 214(3): 847-855.

［8］Dubey RK, Jackson EK, Gillespie DG, et al. Clinically used estrogens differentially inhibit human aortic smooth muscle cell growth and mitogenactivated protein kinase activity［J］. Arterioscler Thromb Vasc Biol, 2000, 20(4): 964-972.

［9］Amant C, Holm P, Xu SH, et al. Estrogen receptormediated, nitric oxidedependent modulation of the immunologic barrier function of the endothelium: regulation of fas ligand expression by estradiol［J］. Circulation, 2001, 104:2576-2581.

［10］Fischer GM, Swain ML. Effect of sex hormones on blood pressure and vascular connective tissue in castrated and noncastrated male rats［J］. Am J Physiol, 1977, 232(6): H617-H621.

［11］Adams MR，Kaplan JR，Manuck SB，et al. Inhibition of coronary artery atherosclerosis by 17beta estradiol in ovariectomized monkeys. Lack of an effect of added progesterone［J］. Arteriosclerosis, 1990, 10(6): 1051-1057.

［12］Li G, Chen YF, Greene GL, et al. Estrogen inhibits vascular smooth muscle celldependent adventitial fibroblast migration in vitro［J］. Circulation,1999, 100:1639-1645.

［13］Hoetzer GL, Stauffer BL, Irmiger HM, et al. Acute and chronic effects of oestrogen on endothelial tissuetype plasminogen activator release in postmenopausal women［J］. J Physiol, 2003, 551(Pt 2):721-728.

［14］White CR, Shelton J, Chen SJ, et al. Estrogen restores endothelial cell function in an experimental model of vascular injury［J］. Circulation, 1997, 96: 1624-1630.

［15］Baskaran C, Stanley N, JeanFranc, et al. Coronary artery endothelial protection after local delivery of 17betaestradiol during balloon angioplasty in a porcine model: A potential new pharmacologic approach to improve endothelial function［J］. J Am Coll Cardiol, 2001, 38(5): 1570-1576.

［16］New G, Moses JW, Roubin GS, et al. Estrogeneluting, phosphorylcholinecoated stent implantation is associated with reduced neointimal formation but no delay in vascular repair in a porcine coronary model［J］. Cathet Cardiovasc Intervent，2002, 57:266-271.

［17］Abizaid A, Albertal M, Costa MA, et al. First human experience with the 17beta estradiol eluting stent: The estrogen and stents to eliminate restenosis (EASTER) trial［J］. J Am Coll Cardiol, 2004, 43(6):1118-1121.

备注/Memo

备注/Memo:
收稿日期：2004-11-08.
更新日期/Last Update: 2010-01-05