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|本期目录/Table of Contents|

白细胞计数与急性心肌梗死患者病死率的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第1期
页码:
67-68
栏目:
临床研究
出版日期:
2006-01-01

文章信息/Info

Title:
Association between leukocyte count and mortality after acute myocardial infarction
作者:
肖骅; 周建庆; 葛世俊; 高丛光; 赵维庆; 陈文采; 柳俊平; 沈文均; 周军波
宁波市医疗中心李惠利医院心内科，浙江 宁波315040
Author(s):
XIAO Hua;  ZHOU Jian-qing;  GE Shi-jun;  GAO Cong-guan;  ZHAO Wei-qing;  CHEN Wen-cai;  LIU Jun-ping;  SHEN Wen-jun;  ZHOU Jun-bo
Department of Cardiology, Ningbo Medical Center Lihuili Hospital, Ningbo， Zhejiang 315040, China
关键词:
心肌梗塞; 急性; 白细胞; 病死率
Keywords:
myocardial infarction;  leukocyte
分类号:
R542.22
DOI:
-
文献标识码:
A
摘要:
目的 研究外周血白细胞总数与急性心肌梗死（AMI）患者病死率的关系，为AMI预后提供预测。 方法 对1994年1月至2004年6月226例AMI患者进行随访（平均417 d）以确定其转归，回顾性分析患者入院时白细胞总数，有关病史及治疗措施。结果 白细胞总数与AMI病死率相关，随着白细胞数的增加，AMI病死率持续增加（P<0.01）。当白细胞数>1.10 ×1010/L时，AMI病死率是≤8.0×109/L时的2.5倍(P<0.01)，0.81~1.10×1010/L时的1.8倍(P<0.05)。 结论 白细胞总数与AMI病死率有关。
Abstract:
AIM To examine the association between peripheral total leukocyte count and mortality in patients with acute myocardial infarction (AMI). METHODS We reviewed 226 AMI patients admitted between January 1994 and June 2004. Followup study was conducted (average 417 day). Multivariable Cox regression analysis and Chisquare analysis were performed to examine the relation between the total leukocyte count and mortality in AMI patients after early therapeutic interventions. RESULTS A highly significant association between leukocyte count and mortality existed as shown by multivariableadjusted regression analysis with demographic and clinical factors controlled. Patients with leukocyte count >1.1×1010/L were at higher risk of death than those with leukocyte count <1.1×1010/L. CONCLUSION Leukocyte count is a prognostic factor associated with increased mortality in patients with AMI.

参考文献/References

［1］ Libby P. Molecular bases of the acute coronary syndromes ［J］. Circulation, 1995, 91: 2844-2850.

［2］ Brown DW, Giles WH, Croft JB. White blood cell count: an independent predictor of coronary heart disease mortality among a national cohort ［J］. J Clin Epidemiol, 2001, 54: 316-322.

［3］ HajjAli R, Zareba W, Ezzeddine R, et al. Relation of the leukocyte count to recurrent cardiac events in stable patients after acute myocardial infarction ［J］. Am J Cardiol, 2001, 88: 1221-1224.

［4］ Cannon CP, McCabe CH, Wilcox RG, et al. Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris ［J］. Am J Cardiol, 2001, 87: 636-639.

［5］ 张玉顺，张进虎，扎拥，等. 冠心病患者中性粒细胞和单核细胞CD11b/CD18表达的研究［J］. 心脏杂志，2001，13（1）：13-15.

［6］ Barron HV, Cannon CP, Murphy SA, et al. Association between white blood cell count, epicardial blood flow, myocardial perfusion, and clinical outcomes in the setting of acute myocardial infarction 10 substudy ［J］. Circulation, 2000, 102: 2329-2334.

［7］ Sabatine MS, Morrow DA, Cannon CP, et al. Relationship between baseline white blood cell count and degree of coronary artery disease and mortality in patients with acute coronary syndromes ［J］. J Am Coll Cardiol, 2002, 40: 1761-1768.

［8］ Barron HV, Harr SD, Radford MJ, et al. The association between white blood cell count and acute myocardial infarction mortality in patients ≥65 years of age: findings from the cooperative cardiovascular project ［J］. J Am Coll Cardiol, 2001, 38: 1654-1661.

备注/Memo

备注/Memo:
收稿日期：2004-11-15.作者简介：肖骅，副主任医师，硕士 Tel:(0574)66826899 Email:xiao.h@163.com
更新日期/Last Update: