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应用组织多普勒成像技术对高血压病左室舒张功能的评估(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第2期
页码:
219-221
栏目:
临床研究
出版日期:
2006-03-01

文章信息/Info

Title:
Assessment of diastolic function in hypertensive patients by Doppler tissue imaging
作者:
吴红宁1; 许迪2; 陆凤翔2; 陈莉2; 周蕾2; 雍永宏2
1. 南京市胸科医院医学影像二科 ，江苏 南京 210029; 2.南京医科大学第一附属医院心内科 ， 江苏 南京 210029
Author(s):
WU Hong-ning1; XU Di2;  LU Feng-xiang2; CHEN Li2; ZHOU Lei2; YONG Yong-hong2
1.Department of Echocardiography, Nanjing Chest Hospital ,Nanjing,Jiangsu,210029，China; 2.Department of Cardiology, First Affiliated Hospital of NJMU, Nanjing, Jiangsu 210029，China
关键词:
组织多普勒成像 ; 高血压; 二尖瓣环;  舒张功能 ; 左室
Keywords:
Doppler tissue imaging;  hypertension;  mitral annular;  diastolic function; left ventricular
分类号:
R544.1
DOI:
-
文献标识码:
A
摘要:
目的 探求无创评价左室舒张功能的新方法。 方法 应用组织多普勒成像（DTI）及脉冲多普勒（PWD）技术检测高血压患者二尖瓣环舒张期运动速度（E、A）及二尖瓣口血流频谱（e、a），并进行对比研究。 结果 ①高血压病患者e、e/a较正常对照组明显降低(P<0.01)，左室等容舒张时间及减速时间显著延长（P<0.01），但左室肥厚（LVH）组与non-LVH组间无显著差异。② 正常人E/A与年龄呈负相关，高血压病患者的相关性减低（P<0.05, P<0.01）。③高血压病患者E、E/A较正常对照组明显减低(P<0.01)，且LVH组比nonLVH组降低更加显著（P<0.01）。④ DTI检测左室充盈假性正常化组二尖瓣环E/A<1。结论 DTI能更准确地测定高血压病患者二尖瓣环舒张期运动速度的改变，评价左室舒张功能受损程度优于传统的血流多普勒法。
Abstract:
AIM To develop a new noninvasive method for quantitative assessment of left ventricular diastolic function. METHODS Mitral annular velocity in early diastole (E), late diastole(A), and mitral inflow velocity e & a in normal and hypertensive patients by Doppler Tissue Imaging (DTI) were detected and compared. RESULTS In hypertensive patients, e and e/a were lower, while DT and IVRT were longer than those of normal. No significant difference was found between patients with left ventricular hypertrophy (LVH) and nonLVH patients. E/A was negatively corelated with age in normal subjects, while poorly related in hypertensive patients. The mitral annular velocity of left ventricular pseudonomal filling (PN) group detected by pulsed DTI is E/A<1. CONCLUSION Doppler tissue imaging can quantify the changes of mitral annular velocity to evaluate the severity of left ventricular dysfunction in hypertensive patients. This method is far better than the conventional Doppler for mitral inflow velocity.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2004-03-10.作者简介：吴红宁，副主任医师，硕士 Tel：（025）837285586138 Email：wuhndr@sina.com
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