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|本期目录/Table of Contents|

他汀类药物对血管重构的干预机制(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2006年第3期
页码:
356-358
栏目:
综述
出版日期:
2006-06-25

文章信息/Info

Title:
-
作者:
汪俊元 王安才
皖南医学院弋矶山医院心内科,安徽 芜湖241001
Author(s):
-
关键词:
他汀类药物血管内皮细胞血管平滑肌细胞细胞外基质血管紧张素II血管内皮生长因子
Keywords:
-
分类号:
R543
DOI:
-
文献标识码:
A
摘要:
他汀类药物对血管重构具有干预作用,本文就其干预机制作一综述。
Abstract:
-

参考文献/References

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[2]Sven W, Ulrich L, Kirsten M, et al. Cellular antioxidant effects of atorvatatin in vitro and in vivo[J]. Aterioscler Thromb Vasc Biol, 2002, 22: 300-305.

[3]刘宇宏,曾秋棠,毛晓波,等. 氟伐他汀防治缺血性心脏病心衰及其抗氧化应激作用的实验研究[J]. 心脏杂志,2005,17(1):21-28.

[4]Seljeflot I, Tonsatd S, Hjermann I, et al. Reduced expression of endothelial cell markers after 1 year treatment with simvastatin and atorvastatin in patients with coronary heart disease[J]. Atherosclerosis, 2002, 162(1): 179-185.

[5]Walter DH, Ritting K, Bahlmann FH, et al. Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrowderived endothelial progenitor cells [J]. Circulation, 2002, 105(25): 3017-3024.

[6]Kishi T, Hirooka Y, Mukai Y, et al. Atorvastatin causes depressor and sympathoinhibitory effects with upregulation of nitric oxide synthase in strokeprone spontaneously hypertensive rats [J]. J Hypertens, 2003, 21(2): 379-386.

[7]季彦,戚文航,高平进,等.辛伐他汀对兔动脉粥样硬化髂动脉TIMP1表达的影响[J].中华心血管病杂志,2002,30(8):500-503.

[8]Luan Z, Chase AJ, Newby AC. statins inhibit secretion of metalloproteinase1、-2、-3 and –9 from vascular smooth muscle cells and macrophages[J]. Arterioscler Thromb Vasc Biol, 2003, 23(5): 769-775.

[9]Gross CM, Gerbaulet S, Quensel S,et al. Agiotensin II type I receptor expression in human coronary arteries with viriable degrees of atheriosclerosis[J]. Basic Res Cardiol, 2002, 97(4): 327-333.

[10]王安才,成蓓,谢小竞,等.阿托伐他汀对自发性高血压大鼠心室重构的影响[J].中国临床药理学与治疗学杂志,2004,9(8):880-884.

[11]Matsuno H, Takei M, Hayashi H, et al. Simvastatin enhance the regeneration of endothelial cells via VEGF secretion in injured arteties[J]. J Cardiovasc Pharmacol, 2004, 43(3): 333-340.

[12]Takenaka M, Hirade K, Tanabe K, et al. Simvastatin stimulates VEGF release via P44/P42 MAP kinase in vascular smooth muscle cells[J]. Biochem Biophys Res Commun, 2003, 301(1): 198-203.

[13]Albert HF, Dulak J, Frick M, et al. Atorvastatin decreases vascular endothelial growth factor in patients with coronary artery disease[J]. J Am Coll Cardiol, 2002, 39(12): 1951-1955.

[14]张路,吴宗贵,黄越承,等.辛伐他汀对人脐静脉内皮细胞血管内皮生长因子表达的影响[J]. 中国动脉硬化杂志,2004,12(4):423-426.

[15]Saijonmaa O, Nyman T, Stewen P, et al. Atorvastatin completely inhibits VEGFinduced ACE upregulation in human endothelial cells[J]. Am J Physiol Heart Circ Physiol, 2004, 286(6): H2096-H2102.

[16]黄芸,戴闺柱,冯宗忱,等. 高脂血症患者低密度脂蛋白氧化易感性及调脂药物干预的影响[J].中华心血管病杂志,2002,30(9):542-544.

备注/Memo

备注/Memo:
收稿日期:2005-07-20.通讯作者:王安才,主任医师,主要从事高血压及冠心病的防治研究 Email:yjswac@sina.com. 作者简介:汪俊元,住院医师,硕士生 Tel:(0533)3861284 Email:wjycom123yahoo.com.cn.
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