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Title:: -

作者:: 易卫平综述; 邱汉婴审校; 汕头大学医学院附属第二医院心内科，广东汕头 515041

Author(s):: -

关键词:: 低钾; 心室颤动; 心律失常

Keywords:: -

分类号:: R591.1; R541.7

DOI:: -

文献标识码:: A

摘要:: 低钾是临床实践中最常见的电解质紊乱之一，常引起心律失常，特别是威胁生命的室性心动过速或心室颤动。本文就低钾触发心室颤动的可能机制和相应的变化，如细胞形态、代谢、能量、电生理及离子通道等方面的研究作一综述。

Abstract:: -

参考文献/References

［1］ Cohn JN, Kowey PR, Whelton PK, et al. New guildines for potassium replacement in clinical practice:A contemporary review by the national council on potassium in clinical practice［J］. Arch Intern Med, 2000，160（16）:2 429-2 437.

［2］ Podrid PJ. Potassium and ventricular arrhythmias［J］. Am J Cardiol， 1990, 65(10): 33E-44E.

［3］ Tribulova N, Manoach M, Varon D, et al. Hypokalemiainduced ultrastructural, histochemical and connexin43 alternations resulting in atrial and ventricular fibrillation［J］. Gen Physiol Biopyhs， 1999， 18 (suppl 1): 15-18，22-23.

［4］ Wolk R, Kane KA, Cobbe SM, et al. Apextobase dispersion of refractoriness underlies the proarrhythmic effect of hypokalemia in the rebbit heart［J］. J Electrocardiol， 2002, 35 (3): 245-252.

［5］ Wan X, Bryant SM, Hart G. The effects of ［K+］o on regional differences in electrical characteristics of ventricular myocytes in guineapig［J］. Exp Physiol， 2000， 85 (6): 769-774.

［6］ Tribulova N, Manoach M, Varon D, et al. Dispersion of celltocell uncoupling precede low K+induced ventricular fibrillation［J］. Physiol Res, 2001, 50(3): 247-259.

［7］ Tribulova N, Okruhlicova L, Novakova S, et al. Hypertensionrelated intermyocyte junction remodeling is associated with a high incidence of low K+induced lethal arrhythmias in isolated rat heart［J］. Exp Physiol， 2002， 87 (2): 195-205.

［8］ Fabritz L, Kirchhof P, Franz MR, et al. Prolonged action potential durations,increased dispersion of repolarization, and polymorphic ventricular tachycardia in a mouse model of proarrhythmia［J］. Basic Res Cardiol， 2003， 98 (1): 25-32.

［9］ Cordeiro J.M, Spitzer K W, Giles W R. Repolarizing K+ currents in rabbit heart Purkinje cells［J］. J Physiolo， 1998, 508(3):811-823.

［10］Kubota T, Shimizu W, Kamakura S, et al. Hypokalemiainduced long QT syndrome with an underlying novel missense mutation in S4S5 linker of KCNQ1 ［J］. J Cardiovasc Electrophysiol， 2000, 11(9):1 048-1 054.

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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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