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Title:: -

作者:: 杨颖; 程龙献; 邬堂春; 廖玉华; 华中科技大学同济医学院附属协和医院心内科，湖北武汉 430022

Author(s):: -

关键词:: 炎症因子; 基因多态性; 冠状动脉疾病

Keywords:: -

分类号:: R541.4;Q343.13

DOI:: -

文献标识码:: A

摘要:: 冠状动脉粥样硬化（AS）是冠心病的病理基础。近年来的研究表明，炎症因子在AS斑块的发生、演变及破裂过程中起到至关重要的作用。本文作者旨在综述某些炎症因子的基因多态性与冠心病的关系。

Abstract:: -

参考文献/References

［1］ Auer J,Weber T,Berent R,et al. Genetic polymorphisms in cytokine and adhesion molecule genes in coronary artery disease［J］.Am J Pharmacogenomics,2003,3(5):317-328.

［2］ Allen RA,Lee EM,Roberts DH,et al. Polymorphisms in the TNFalpha and TNFreceptor genes in patients with coronary artery disease［J］. Eur J Clin Invest,2001,31(10):843-851.

［3］ Andreotti F, Porto I, Crea F, et al. Inflammatory gene polymorphisms and ischaemic heart disease: review of population association studies［J］. Heart，2002,87(2):107-112.

［4］潘晓明，吴宗贵,黄佐，等.TNFα水平对急性心肌梗死预后的影响［J］.心脏杂志，2004，16（1）：39-40.

［5］ David J. Transforming growth factor β and atherosclerosis: so far,so good for the protective cytokine hypothesis［J］. Arterioscler Thromb Vasc Biol,2004,24(3):399-404.

［6］黄荣杰，刘唐威，庞玉生.转化生长因子β1在扩张型心肌病大鼠心肌纤维中的作用［J］. 心脏杂志，2005，17（2）：126-128.

［7］ Iacoviello l,Di Castelnuovo A,Gattone M,et al. Polymorphisms of the interleukin1beta gene affect the risk of myocardial infarction and ischemic stroke at young age and the response of mononuclear cells to stimulation in vitro［J］. Arterioscler Thromb Vasc Biol,2005,25(1): 222-227.

［8］ Hohda S,Kimura A,Sasaoka T,et al. Association study of CD14 polymorphism with myocardial infarction in a Japanese population［J］.Jpn Heart J,2003,44(5):613-622.

［9］陈以初，孙健，廖树森 ,等.急性冠脉综合征患者血浆P选择素的变化及意义［J］.心脏杂志，2004，16（1）：41-42.

［10］Yoshida M,Takano Y,Sasaoka T, et al. Eselectin polymorphism associated with myocardial infarction causes enhanced leukocyte endothelial interactions under flow conditions［J］. Arterioscler Thromb. Vasc Biol,2003,23(5):783-788.

［11］Fang L, Wei H, Chowdhury SH, et al. Association of Leu125Val polymorphism of platelet endothelial cell adhesion molecule1 (PECAM1) gene & soluble level of PECAM1 with coronary artery disease in Asian Indians［J］.Indian J Med Res,2005,121(2):92-99.

［12］Listi F,Candore G,Lio D,et al. Association between platelet endothelial cellular adhesion molecule 1 (PECAM1/CD31) polymorphisms and acute myocardial infarction: a study in patients from Sicily［J］.Eur J Immunogenet,2004,31(4):175-178.

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某些炎症因子基因多态性与冠心病关系的研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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