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¡¶ÐÄÔàÔÓÖ¾¡·[ISSN:1009-7236/CN:61-1268/R]

ÆÚÊý:

2007ÄêµÚ1ÆÚ

Ò³Âë:

45-47

À¸Ä¿:

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³ö°æÈÕÆÚ:

2007-01-01

ÎÄÕÂÐÅÏ¢/Info

Title:

Changes of myocardial perfusion levels after percutaneous coronary intervention in coronary artery disease patients with different stenosis degrees

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Íõºì¹;  »Æá°¹ ;  ½ú¾ü¹ ;  ËÎÒ«Ã÷¹ ;  ¹¢ÕÙ»ª¹ ;  ÓÚѧ¾ü¹ ;  ñû¾ü¹;  ÕÔ¸Õ¹;  ¸ßÔÆ»ª²;  ÁõÕþ² ;  ÑîÀò²

µÚÈý¾üÒ½´óѧ¸½ÊôÐÂÇÅÒ½Ôº£º1. È«¾üÐÄѪ¹ÜÄÚ¿ÆÖÐÐÄ,2. ³¬Éù¿Æ£¬ÖØÇì 400037

Author(s):

WANG Hong¹;  HUANG Lan¹;  JIN Jun¹;  SONG Yaoª²ming¹;  GENG Shaoª²hua¹;  YU Xueª²jun¹;  QIN Jun¹;  ZHAO Gang¹;  GAO Yunª²hua²;  LIU Zheng²; YANG Li²

1.PLA Cardiologic Center, 2.Department of Ultrasound, Xingqiao Hosipital, Third Military Medical University, Chongqing 400037, China

¹Ø¼ü´Ê:

¹Ú×´¶¯Âö¼²²¡;  ¾­Æ¤¹Ú×´¶¯Âö½éÈëÊõ;  Ðļ¡¹à×¢

Keywords:

coronary disease;  percutaneous coronary intervention;  myocardial perfusion

·ÖÀàºÅ:

R540.45

DOI:

-

ÎÄÏ×±êʶÂë:

A

ÕªÒª:

Ä¿µÄ ÀûÓþ­¹Ú×´¶¯Âö³¬ÉùÐļ¡ÉùѧÔìÓ°£¨MCE£©±È½Ïµ¥Ö§Ñª¹Ü²»Í¬³Ì¶ÈÏÁÕ­²¡±ä¹ÚÐIJ¡»¼Õß¾­Æ¤¹Ú×´¶¯Âö½éÈëÊõ£¨PCI£©ºóÐļ¡¹à×¢µÄ±ä»¯£¬²¢Ì½ÌÖÆäÁÙ´²ÒâÒå¡£ ·½·¨ 62Àý½øÐÐPCIÖÎÁƵÄסԺ»¼Õ߸ù¾ÝÑ¡ÔñÐÔ¹Ú×´¶¯ÂöÔìÓ°½á¹û£¬°´Ñª¹ÜÏÁÕ­³Ì¶È·Ö×飺A×飬Ѫ¹ÜÏÁÕ­75%¡«95%£»B×飬Ѫ¹ÜÏÁÕ­>95%£»C×飬¼±ÐÔѪ¹Ü±ÕÈû¡£PCIÇ°¼°Êõºó15 min½øÐо­¹Ú×´¶¯ÂöMCE£¬¼ì²âÐļ¡¹à×¢×´¿ö¡£ÆäÖÐ,MCEÓйض¨Á¿²ÎÊý·Ö±ðΪ£ºÔìÓ°¼Á·åÖµÃܶȷ´Ó³Ðļ¡ÑªÈÝÁ¿£»·åֵʱ¼ä·´Ó³Ðļ¡¹à×¢Ëٶȣ»ÇúÏßÏÂÃæ»ý·´Ó³Ðļ¡ÑªÁ÷Á¿¡£ ½á¹û ËùÓл¼ÕßPCIºó¾ù´ïµ½TIMI ¢ó¼¶ÑªÁ÷£» A×éÊõºóÐļ¡ÑªÁ÷Á¿½ÏÊõÇ°Ôö¼Ó£¨P<0.05£©£»B×éÐļ¡ÑªÈÝÁ¿¼°ÑªÁ÷Á¿Ò²½ÏÊõÇ°Ôö¼Ó£¨P<0.05£©£»¶øC×éÐļ¡ÑªÈÝÁ¿¡¢ÑªÁ÷Á¿¼°¹à×¢ËٶȽÏÊõÇ°Ôö¼Ó¸üÏÔÖø£¨P<0.01£©¡£ ½áÂÛ ²»Í¬ÏÁÕ­³Ì¶È²¡±ä¹ÚÐIJ¡»¼Õߣ¬PCIºóÐļ¡¹à×¢¾ùµÃµ½²»Í¬³Ì¶È¸ÄÉÆ£¬ÆäÖУ¬ÒÔ¼±ÐÔ±ÕÈû²¡±ä¸ÄÉÆ×îÃ÷ÏÔ£¬¸ÃÀ໼ÕßΪPCIÖÎÁƵÄ×î´ó»ñÒæÕß¡£

Abstract:

AIM To investigate the changes of myocardial perfusion after percutaneous coronary intervention in coronary artery disease patients with different degree of stenosis by quantitative intracoronary myocardial contrast echocardiography (MCE). METHODS Sixtyª²two patients were divided in to three groups according to the results of selective coronary angiography: group A with coronary artery stenosis 75%~95%, group B with coronary artery stenosis >95% and group C with coronary acute total occlusion. Myocardial reperfusion levels were evaluated before and 15 min after PCI. The quantitative parameters of MCE were analyzed, including contrast peak intensity (A), time to peak intensity (TP) and area under the curve (AUC), representing myocardial blood volume, reperfusion velocity and myocardial blood flow respectively. RESULTS All the target vessels achieved TIMI grade 3 flow after PCI and myocardial blood flow in group A increased after PCI£¨P<0.05£©. Both myocardial blood volume and blood flow also increased in group B£¨P<0.05£©. Significant changes were found in all the parameters of MCE inflecting the levels of myocardial perfusion in group C£¨P<0.01£©. CONCLUSION The myocardial perfusion levels are enhanced to different degrees after successful PCI in patients with differentª²degree stenosis artery and the change in acute myocardial infarction patients is the most obvious.

²Î¿¼ÎÄÏ×/References

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