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血浆脑钠尿肽及TIMI危险评分对急性心肌梗死患者的预后价值(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2007年第1期
页码:
60-61/64
栏目:
临床研究
出版日期:
2007-01-01

文章信息/Info

Title:
Prognostic value of brain natriuretic peptide and TIMI risk score in patients with acute myocardial infarction
作者:
吴士礼 ; 包宗明; 张恒; 史晓俊; 王洪巨
蚌埠医学院附属医院心内科，安徽 蚌埠 233004
Author(s):
WU Shili;  BAO Zongming;  ZHANG Heng;  SHI Xiaojun;  WANG Hongju
Department of Cardiology, Affiliated Hospital of Bengbu Medical College, Bengbu 233004 Anhui, China
关键词:
脑钠尿肽; TIMI危险评分; 心肌梗塞; 急性; 预后
Keywords:
brain natriuretic peptide;  TIMI risk score;  myocardial infarction; Acute;  prognosis
分类号:
R542.22
DOI:
-
文献标识码:
A
摘要:
目的 评估血浆脑钠尿肽（BNP）联合TIMI危险评分对急性心肌梗死(AMI)患者预后价值。方法 集中检测连续收入院且随访资料齐全的63例AMI患者血浆BNP，按TIMI危险评分的多个临床资料分析记分，将患者分成不同的危险层次，分析患者BNP水平及TIMI危险评分与患者3个月随访期主要不良心血管事件发生的关系。 结果 15例复合心血管事件中BNP≥137 pg/ml者占11例，随着BNP水平增高，患者的主要心血管事件发生率也增多,且随着TIMI危险评分值增加而逐渐升高。结论 BNP水平和TIMI危险评分越高，临床预后越差。
Abstract:
AIM To evaluate the prognostic value of the combination of brain natriuretic peptide (BNP) and thrombolysis in myocardial infarction (TIMI) risk scoring system in patients with acute myocardial infarction (AMI). METHODS Centralized measurements of BNP were performed after admission in 63 consecutive patients with AMI. TIMI risk scores were calculated from clinical data and risk stratification of patients was conducted according to the scores. The relation of BNP and TIMI risk scores and major adverse cardiovascular events (MACE) from a 3month follow up were analyzed. RESULTS 11 cases out of the 15 patients with cardiac events were distributed in patients with BNP level over 137 pg/ml. Among these highrisk patients, the incidence of MACE increased significantly with the rise of TIMI risk score. CONCLUSION The higher the BNP level and TIMI risk score, the worse the prognosis.

参考文献/References

［1］中华医学会心血管病学分会，中华心血管病杂志编辑委员会，中国循环杂志编辑委员会. 急性心肌梗死诊断和治疗指南［J］. 中华心血管病杂志，2001，29（12）：710-725.

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［5］黄高忠，顾军，汤晔华，等. 急性心肌梗死患者血脑钠尿肽前体N末端的变化［J］. 心脏杂志，2005，17（5）：468-470.

［6］De Lemos JA, Morrow DA, Bentley JH, et al. Prognostic value of Btype natriuretic peptide in patients with acute coronary syndromes［J］. New Eng J Med, 2001, 345(14):1014-1021.

［7］卢飞舟，赵殿有.充血性心力衰竭患者血浆脑钠素浓度与心功能的关系［J］.心脏杂志，2004，16（3）：266-267.

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备注/Memo

备注/Memo:
收稿日期：2005-11-23.作者简介：吴士礼，主治医师，硕士Email：chnwsl@126.com
更新日期/Last Update: