我们的网站为什么显示成这样?

可能因为您的浏览器不支持样式,您可以更新您的浏览器到最新版本,以获取对此功能的支持,访问下面的网站,获取关于浏览器的信息:

|本期目录/Table of Contents|

急性心肌梗死患者纤维蛋白原含量与冠状动脉病变程度及预后有关(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2007年第1期
页码:
65-66
栏目:
临床研究
出版日期:
2007-01-01

文章信息/Info

Title:
Fibrinogen is associated with severity of coronary artery disease and prognosis in acute myocardial infarction
作者:
肖军唐发宽王龙
解放军总医院第二附属医院心内科,北京 100091
Author(s):
XIAO Jun TANG Fakuan WANG Long
Department of Cardiology, Second Affiliated Hospital, PLA General Hospital, Beijing 100091, China
关键词:
心肌梗塞急性纤维蛋白原冠状动脉疾病
Keywords:
myocardial infarction acute fibrinogencoronary disease
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 探讨纤维蛋白原(FIB)含量与急性心肌梗死(AMI)冠脉病变程度及预后的关系。方法 根据AMI初期FIB含量将90例AMI分为两组,A组FIB值>4 g/L, B组FIB值≤4 g/L。将两组冠脉造影结果及预后进行比较分析。结果 A组多支血管病变33例(占73%)、梗死相关血管近端病变36例(占80%)、心力衰竭10例(占22%)、严重心律失常14例(占31%)、梗死后心绞痛11例(占24%),与B组分项比较差异显著(P<0.05)。结论 FIB增多的急性AMI多为多支血管病变,梗死相关血管多为近端病变,预后不好。
Abstract:
AIM To explore the relation between the severity of coronary artery disease, prognosis and fibrinogen in acute myocardial infarction (AMI). METHODS Ninety patients with AMI were divided into two groups (group A: fibrinogen >4 g/L, group B: fibrinogen≤4 g/L) based on fibrinogen. The data of both groups were compared with coronary angiographic findings and prognosis. RESULTS In group A, there were 33 (73%) multivessel disease, 36 (80%) proximal lesions of infarction related artery, 10 (22%) cases of heart failure, 14 (31%) cases of serious cardiac arrhythmia, and 11 (24%) cases of postinfarction angina pectoris. There was significant difference in above indexes between group A and group B (P<0.05). CONCLUSION Multivessel disease, proximal lesion of infarction related artery and poor prognosis are found in patients with AMI with high fibrinogen.

参考文献/References

[1]张剑,韩雅玲,康建,等. 纤维蛋白原与冠心病类型、危险因素及病变的相关性[J].心脏杂志,2003,15(2):134 -136.

[2]戴菁,王明山. 心肌缺血/再灌注损伤时抗凝血酶和纤维蛋白原的变化[J].心脏杂志,2002,14(4):301-304.

[3]Guidelines Subcommittee.1999 World Health Organization international society of hypertension guidelines for the management of hypertension. Guidelines Subcommittee[J]. J Hypertens,1999,17(2):151-183.

[4]Hamsten A. The hemostatic system and coronary heart disease [J]. Thromb Res,1993,70(1):1-38.

[5 ]王雪青. 纤维蛋白(原)在动脉粥样硬化发病中的作用及机制[J].生理科学进展,1996,27(3):245-248.

[6]马建林,毛焕元. 老年血栓形成前状态及其防治的研究进展[J].心脏杂志,2002,14(2):170-172.

备注/Memo

备注/Memo:
收稿日期:2006-06-30.作者简介:肖军,硕士生,主治医师Email:xxxjjj6288@sina.com
更新日期/Last Update: