血浆纤维蛋白原和D二聚体水平与冠状动脉病变程度的相关研究(PDF)
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2007年第3期
- 页码:
- 309-310/325
- 栏目:
- 临床研究
- 出版日期:
- 2007-06-01
文章信息/Info
- Title:
- Correlation between plasma fibrinogen and Ddimer level and pathological changes of coronary artery
- Author(s):
- LU Yuliang; QIU Shengqiang; YANG Xiangjun
- Department of Cardiology, Huzhou Central Hospital, Huzhou 313000, Zhejiang,China
- Keywords:
- coronary disease; fibrinogen; Ddimer
- 分类号:
- R 541.4
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 目的 研究血浆纤维蛋白原(FG)和D二聚体(DD)水平与冠心病患者冠状动脉病变程度的相关性。方法 分别测定18例急性心肌梗死患者，23例不稳定型心绞痛患者，34例稳定型心绞痛患者和对照组58例患者中的FG和DD含量，并根据冠脉造影结果将冠心病组分为单支病变组25例，两支病变组21例，三支病变组29例。结果 冠脉两、三支病变组FG和DD含量显著高于对照组和一支病变组（P<0.01），三支病变组显著高于两支病变组（P<0.05），对照组和一支病变组差异无显著性。结论 冠心病患者血浆纤维蛋白原和D二聚体较正常对照组显著升高，其值愈高，冠脉病变愈重。
- Abstract:
- AIM To explore the correlation between the level of the plasma fibrinogen (FG) and Ddimer (DD) and the pathological changes of coronary arteries. METHODS FG and DD were measured respectively in 18 patients with acute myocardial infarction (AMI group), 23 patients with unstable angina (UA group), 34 patients with stable angina (SA group) and 58 control cases. According to the results of coronary angiography, 75 patients with coronary heart disease were divided into 25 patients with singlevessel group, 21 patients with doublevessel group and 29 patients with triplevessel group. RESLUTS The concentration of FG and DD in patients with double and triplevessel groups were significantly higher than that in patients with singlevessel group and control group (P<0.01). Compared with that in the doublevessel group, the level of fibrinogen in triplevessel group was higher (P<0.05). No significantly difference was found in DD and FG levels in patients between singlevessel and control groups. CONCLUSION The higher level of the plasma fibrinogen and Ddimer may suggest the severer pathological changes of coronary arteries.
参考文献/References
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备注/Memo
- 备注/Memo:
- 收稿日期：2006-03-13 通讯作者：杨向军, 教授，主要从事心血管介入治疗研究Email:yxjdemail@163.net作者简介：陆玉良，主治医师Email: anyonlylylboy@163.com
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