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|本期目录/Table of Contents|

影响2型糖尿病患者自主神经功能的相关因素(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2007年第6期
页码:
672-674
栏目:
临床研究
出版日期:
2007-12-20

文章信息/Info

Title:
Multiple risk factors of autonomic neuropathy in type 2 diabetic patients
作者:
张国庆1徐世全2许樟荣2王玉珍2陆祖谦2张秀芬1李臻1
解放军第306医院:1.特诊科,2.糖尿病中心,北京100101
Author(s):
ZHANG Guo-qing XU Shi-quan XU Zhang-rong WANG Yu-zhen LU Zu-qian ZHANG Xiu-fen LI zhen
Center of Diabetes,306th Hospital of PLA, Beijing 100101, China
关键词:
糖尿病2型 自主神经 心率变异性 危险因素 非条件Logistic回归分析
Keywords:
Type 2 diabetes autonomic neuropathy heart rate variability risk factor Logistic regressionanalysis
分类号:
R587.1
DOI:
-
文献标识码:
A
摘要:
目的 探讨影响2型糖尿病(T2DM)患者自主神经功能的相关因素。方法 将T2DM患者按心率变异性(HRV)分为HRV正常组和降低组,并调查检测和收集了患者的年龄、糖尿病病程、冠心病病程、高血压病程、脑血管病病程、血脂和血糖等资料。结果 用单因素非条件Logistic回归分析发现HRV降低与年龄、DM病程、冠心病、收缩压、脉压、三酰甘油、尿素氮、肌酐、尿微量白蛋白及DM视网膜病变有关(P<0.05,P<0.01)。用多因素非条件logistic回归筛选分析,年龄、三酰甘油、尿素氮、DM视网膜病变是影响DM患者自主神经功能的相关因素。结论 T2DM患者自主神经功能与患者年龄、三酰甘油、尿素氮和DM视网膜病变有关联 。
Abstract:
AIM To study the heart rate variability (HRV) and related risk factors in type 2 diabetic patients. METHODS Patients with type 2 diabetes were divided into normal and decreased HRV group according to HRV. The baseline data were collected, including age, duration of type 2 diabetes, coronary artery diseases, hypertension and cerebral vessel diseases, lipid profile, and serum fasting glucose. RESULTS Univariate unconditional logistic regression analysis showed that decreased HRV was related to the age, duration of diabetes, coronary artery diseases, systolic blood pressure, pulse pressure, TG (triglyceride), BUN (blood urea nitrogen), sCR (serum creatinine,) UAE (urinary albumin excretion), and diabetic retinopathy of the patients (P<0.05,P<0.01). Multivariate unconditional logistic regression analysis indicated that diabetic autonomic neuropathy was related to the age, TG, BUN, and diabetic retinopathy of the patients. CONCLUSION Autonomic neuropathy in type 2 diabetes is correlated to the age, TG, BUN, and diabetic retinopathy of the patients.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期:2006-08-21.作者简介:张国庆,副主任医师 Email:zhanggq5608@sina.com
更新日期/Last Update: