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［1］ Joubert S, Jossart C, McNicoll N,et al.Atrial natriuretic peptidedependent photolabeling of a regulatory ATPbinding site on the natriuretic peptide receptorA［J］.FEBS J, 2005,272(21):5572 -5583.

［2］ Nishikimi T, Hagaman JR, Takahashi N,et al. Increased susceptibility to heart failure in response to volume overload in mice lacking natriuretic peptide receptorA gene［J］.Cardiovasc Res, 2005,66(1):94-103.

［3］ Ito T, Yoshimura M, Nakamura S,et al. Inhibitory effect of natriuretic peptides on aldosterone synthase gene expression in cultured neonatal rat cardiocytes［J］.Circulation, 2003,107(6):807-810.

［4］ Vellaichamy E, Sommana NK, Pandey KN. Reduced cGMP signaling activates NFκB in hypertrophied hearts of mice lacking natriuretic peptide receptorA［J］.Biochem Biophys Res Commun, 2005,327(1):106-111.

［5］ Kilic A, Velic A, De Windt LJ,et al.Enhanced Activity of the Myocardial Na+/H+ Exchanger NHE1 Contributes to Cardiac Remodeling in Atrial Natriuretic Peptide ReceptorDeficient Mice［J］.Circulation, 2005,112(15):2307-2317.

［6］ Tokudome T, Horio T, Kishimoto I,et al.CalcineurinNuclear Factor of Activated T Cells PathwayDependent Cardiac Remodeling in Mice Deficient in Guanylyl Cyclase A, a Receptor for Atrial and Brain Natriuretic Peptides ［J］.Circulation.2005,111(23):3095-3104.

［7］ Zahabi A, Picard S, Fortin N,et al. Expression of Constitutively Active Guanylate Cyclase in Cardiomyocytes Inhibits the Hypertrophic Effects of Isoproterenol and Aortic Constriction on Mouse Hearts［J］. J Biol Chem, 2003,278(48): 47694-47699.

［8］ Horio T, Tokudome T, Maki T,et al. Gene Expression, Secretion, and Autocrine Action of CType Natriuretic Peptide in Cultured Adult Rat Cardiac Fibroblasts ［J］.Endocrinology, 2003, 144(6): 2279-2284.

［9］ Langenickel TH, Buttgereit J, PagelLangenickel I,et al. Cardiac hypertrophy in transgenic rats expressing a dominantnegative mutant of the natriuretic peptide receptor B［J］.Proc Natl Acad Sci U S A, 2006,103(12):4735-4740.

［10］Hum D, Besnard S, Sanchez R,et al.Characterization of a cGMPresponse element in the guanyly cyclase/natriuretic peptide receptor a gene promoter［J］.Hypertension, 2004,43(6):1270-1278.

［11］Kuhn M, Voss M, Mitko D,et al. Left ventricular assist device support reverses altered cardiac expression and function of natriuretic peptides and receptors in endstage heart failure［J］.Cardiovasc Res, 2004,64(2):308-314.

［12］Hawkridge AM, Heublein DM, Bergen HR,et al. Quantitative mass spectral evidence for the absence of circulating brain natriuretic peptide (BNP32) in severe human heart failure［J］.Proc Natl Acad Sci U S A, 2005,102(48):17442-17447.

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《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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