国产室间隔缺损封堵器与Amplatzer封堵器的疗效比较(PDF)
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2008年第1期
- 页码:
- 68-70
- 栏目:
- 临床研究
- 出版日期:
- 2008-01-20
文章信息/Info
- Title:
- Transcatheter closure of ventricular septal defect: Comparison of Amplatzer septal occluder and a Chinamade septal occluder
- Author(s):
- WANG Wei; ZENG Guohong; ZHANG Zhiwei; LI Yufen; SHI Jijun; LI Junjie; XIE Yumei
- Department of Pediatrics, Guangdong Cardiovascular Institute, Guangdong Provincial people′s hospital, Guangzhou 510100, Guangdong, China
- 分类号:
- R541.1
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 目的 比较国产室间隔缺损封堵器与Amplatzer封堵器在经导管室间隔缺损封堵术中的疗效。方法 41例患儿采用Amplatzer封堵器，76例患儿采用国产封堵器进行室间隔缺损封堵术，对比两组的疗效、并发症和费用等情况。结果 国产组75例封堵成功（成功率99%），进口组40例封堵成功（成功率98%）。两组患儿术前各项临床指标、手术和X线曝光时间、封堵成功率及住院天数，术后各项并发症发生率比较差异无统计学意义，两组患儿治疗前后左室舒张末径、收缩末径及C/T值减少程度无明显差异，治疗总费用进口组明显高于国产组。结论 国产室间隔缺损封堵器与Amplatzer封堵器相比较其疗效、并发症发生率无显著差异，治疗费用低，临床应用前景广泛。
- Abstract:
- AIM To compare the efficiency of transcatheter closure of ventricular septal defect by using Amplatzer septal occluder and a new septal occluder made in China. METHODS Fortyone patients were treated with Amplatzer septal occluder and 76 patients were treated with a Chinamade septal occluder during the same period. The efficiency, complications and cost of both groups were compared. RESULTS No significant difference was found in comparing the preoperatively clinical indexes, operative and exposure time, hospital days and the rate of complete closure and complication. No significant difference was found in the decrease of left ventricular systolic and diastolic end, as well as C/T. The total cost of the Amplatzer septal occluder group was much higher than that of the Chinamade septal occluder group. CONCLUSION There is no significant difference in the rate of complete closure and complications between using Amplatzer septal occluder or the Chinamade septal occluder in treating ventricular septal defect. The Chinamade septal occluder is safe and effective for transcatheter closure of ventricular septal defect.
参考文献/References
［1］ Lock JE, Block PC, Mckay RG, et al. Transcatheter closure of ventricular septal defects［J］. Circulation,1988,78(2):361-368.
［2］ Hijazi ZM, Hakim F, Haweleh AA, et al. Catheter closure of permembranous ventricular septal defects using the new Amplatzer membranous VSD occluder: Initinal clinical experience［J］. Catheter Cardiovasc Interv, 2002,56(4):508-515.
［3］ 张智伟，曾国洪，林曙光，等.国产膜周部室间隔缺损封堵器的研制及临床应用［J］. 中华心血管病杂志.2005，3（12）：228-231.
［4］ Sideris EB, Walsh KP, Haddad JL, et al. Occlusion of congenital ventricular septal defects by the buttoned device "Buttoned device". Clinical Trials International Register［J］. Heart,1997,77(3):276-279.
［5］ Bauer JJ, Harris MT, Kreel I, et al. Twelveyear experience with expanded polytetrafluoroethylene in the repair of abdominal wall defects［J］. Mt Sinai J Med,1999,66(1):20-25.
备注/Memo
- 备注/Memo:
- 收稿日期：2006-09-07.作者简介：王威，硕士生Email:wang781231@tom.com
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