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Title:: -

作者:: 孙颖综述; 常志文审校; 首都医科大学附属北京同仁医院干部医疗科，北京 100730

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关键词:: 清道夫受体; CD36; 动脉粥样硬化

Keywords:: -

分类号:: R541.4

DOI:: -

文献标识码:: A

摘要:: B类清道夫受体（SR）CD36是一个分布广泛,生物作用多样的多配基受体，参与体内多种病理、生理过程。在动脉粥样硬化（AS）形成过程中其介导单核细胞与内皮细胞黏附，是单核－巨噬细胞识别、内吞oxLDL的主要SR，参与泡沫细胞和AS形成。CD36表达的调控机制一直是研究的热点，特别是PPARγ的作用，而相关药物如临床上广泛应用的作为胰岛素增敏剂的PPARγ激动剂以及他汀类降脂药等对CD36表达的影响也引起人们的关注。

Abstract:: -

参考文献/References

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B类清道夫受体CD36与动脉粥样硬化研究进展(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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