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冠状动脉造影确诊的女性冠心病患者临床特点和病变特征

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第1期
页码:
92
栏目:
临床研究
出版日期:
2009-02-28

文章信息/Info

Title:
Clinical and coronary lesion characteristics in female coronary heart disease patients diagnosed by coronary arteriography
作者:
卢敏
东莞市黄江医院内二科，广东 东莞 523750
Author(s):
LU Min
Second Department of Internal Medicine, Huangjiang Hospital, Dongguan 523750, Guangdong, China
关键词:
女性; 冠状动脉造影术; 冠状动脉疾病; 危险因素
Keywords:
female;  coronary arteriography;  coronary disease;  risk factors
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的 探讨女性冠心病患者的临床及冠状动脉病变特点。方法 将冠脉造影确诊的73例女性冠心病患者与同期造影确诊的男性冠心病患者的临床资料、危险因素及冠脉病变特点和血肌钙蛋白T、C反应蛋白、纤维蛋白原浓度相互比较分析。结果 女性组冠心病患者的年龄较大、典型胸痛症状和冠心病危险因素个数较男性组低，大腹围、糖尿病史、高血清胆固醇、低高密度脂蛋白及心电图缺血改变的比例较男性组高，血低密度脂蛋白、C反应蛋白和纤维蛋白原及心肌肌钙蛋白T水平与男性组无明显差别。女性冠脉单支病变比例高于男性组，Gensini计分低于男性组。结论 女性冠心病患者胸痛症状不典型，心电图异常检出比例高，冠心病危险因素和冠脉病变程度相对于男性较低。
Abstract:
AIM To investigate the difference of the risk factors and coronary lesion characteristics in female and male patients with heart disease. METHODS Seventy-three female and 172 male patients, who had been diagnosed CHD by positive coronary angiography from Jan. 2003 to Dec. 2005, were included in the study. Their numbers of branches, extent and Gensini cumulative index of coronary lesions, clinic characteristics and risk factors, the levels of cardiac troponin T, C reactive protein and fibrinogen were comparatively analyzed. Cardiovascular risk factors included age, gender, history of family, hypertension, smoking, type 2 diabetes mellitus and dyslipidemia. RESULTS Compared with those in male group, the female group had older age, longer abdomen circumference, less typical angina and fewer numbers of risk factors, higher the levels of blood cholesterol, high-density lipoprotein, fasting serum glucose and rate of ECG abnormality, but lower triglyceride. No significant difference was seen in the levels of cardiac troponin T, C reactive protein and fibrinogen between female group and male group. The female group had fewer the branches of coronary lesion and lower Gensini cumulative index of coronary lesions. CONCLUSION Female coronary heart disease patients tend to have atypical angina but the detectable ECG rate is higher. Compared with their male counterparts, female coronary heart disease patients have fewer risk factors and less severe abnormality.

参考文献/References

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［3］ 王正东，李醒三，李平. 女性冠心病患者的临床特点［J］. 中国动脉硬化杂志, 2003， 11（7）：663-664.
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［5］ 徐远溪,邢燕,赵明中，等. 冠状动脉病变程度与冠心病危险因素的关系［J］. 同济大学学报（医学版）, 2007, 28（1）:83-88.
［6］ 卢敏，张梦玺. 冠心病患者肺炎衣原体感染与C反应蛋白、纤维蛋白原相互关系的研究［J］. 中国抗感染化疗杂志， 2002， 2（1）：10-12.
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备注/Memo

备注/Memo:
收稿日期：2007-12-10.基金项目：湖南省益阳市科技奖项目资助（20050106） 作者简介：卢敏，副主任医师，硕士Email:iyming2001@163.com
更新日期/Last Update: 2009-04-02