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性别对ST段抬高的急性心肌梗死急诊冠脉介入治疗预后的影响

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第5期
页码:
696-698
栏目:
临床研究
出版日期:
2009-07-14

文章信息/Info

Title:
Impact of gender on prognosis of patients with ST-elevated acute myocardial infarction treated with percutaneous coronary intervention
作者:
李东宝; 华琦; 刘志; 王珊; 金尉英
首都医科大学宣武医院心脏科，北京 100053
Author(s):
LI Dong-bao;  HUA Qi;  LIU Zhi;  WANG Shan;  JIN Wei-ying
Department of Cardiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
关键词:
性别; 经皮冠脉介入治疗; ST段抬高心肌梗死
Keywords:
gender;  emergency percutaneous coronary intervention;  ST-elevated acute myocardial infarction
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的: 探讨性别对ST段抬高的急性心肌梗死（STEMI）患者急诊冠脉介入治疗（PCI）预后的影响。方法: 164例STEMI患者急诊PCI后，观察其临床及冠脉介入治疗特征和院内全因死亡率。结果: 女性患者的平均年龄较大，并发糖尿病的比例较高，低密度脂蛋白胆固醇较高，梗死相关血管介入治疗前TIMI Ⅲ级血流的比例较高，而吸烟率和入院时的舒张压明显较低。但两组的梗死相关血管内血栓发生率、PCI后TIMI Ⅲ级血流的比例及院内病死率均无统计学差异。结论: 性别对STEMI患者急诊PCI近期预后无明显影响。
Abstract:
AIM: To investigate the impact of gender on the prognosis of patients with ST-elevated acute myocardial infarction (STEMI) treated with emergency percutaneous coronary intervention (PCI). METHODS: One hundred and sixty four STEMI patients (130 males vs.34 females) who had been treated with emergency PCI were evaluated on clinical and angiographic characteristics and mortality of all causes during hospitalization. RESULTS: Mean age of women was older than that of men, and women had a higher incidence of diabetes mellitus compared with that of men. LDL-C level of women was also higher than that of men. Rate of smokers and diastolic pressure on admission were lower. No significant difference was observed between genders in mortality, rate of thrombus in infarct-related artery and percentage of TIMI III flow after PCI. CONCLUSION: Gender had no obvious effect on the short-term prognosis of STEMI patients treated with emergency PCI.

参考文献/References

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［10］Lansky AJ, Mehran R, Dangas G, et al. Comparison of difference in outcome after percutaneous coronary intervention in men versus women<40 years of age［J］. Am J Cardiol, 2004, 93(7):916-919.

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［13］Peterson ED, Lansky AJ , Kramer J, et al. Effect of gender on the outcomes of contemporary percutaneous coronary intervention［J］. Am J Card iol, 2001, 88(4):359-364.

［14］郑建勇,李田昌,史旭波. 性别对急性冠脉综合症介入治疗预后的影响［J］. 中国医药导刊, 2007, 9(2):113-115.

备注/Memo

备注/Memo:
收稿日期：2008-10-27.基金项目：国家自然科学基金项目资助(70072032) 通讯作者：华琦，教授，主要从事高血压和冠心病研究Email:huaqi5371@medmail.com.cn 作者简介：李东宝，副主任医师，博士Email:leetobo@sina.com
更新日期/Last Update: 2009-07-22