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|本期目录/Table of Contents|

MicroRNA在心血管疾病中作用的研究进展

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2009年第5期
页码:
730-734
栏目:
综述
出版日期:
2009-07-14

文章信息/Info

Title:
-
作者:
陈婷; 王长谦
上海交通大学附属新华医院心血管内科，上海 200092
Author(s):
-
关键词:
microRNA; 心血管疾病
Keywords:
-
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
microRNA是一类长度在22nt左右、能调节mRNA表达的非编码RNA基因产物。miRNA最初在线虫体内被发现，广泛存在于真核生物体内，对于生物体的发育等诸多方面有调节作用，并在进化中保守。miRNA作用机制尚不完全清楚，但已知其能通过与mRNA的3′端非翻译区结合而影响翻译水平。现就miRNA的生物发生、作用机制及其在心脏发育、心肌肥厚、动脉粥样硬化、心力衰竭、高血压和心律失常中起的作用的研究进展作一综述。
Abstract:
-

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2008-6-17.通讯作者：王长谦：主任医师，主要从事冠状动脉粥样硬化防治的研究Email：wcqian@hotmail.com 作者简介：陈婷，住院医师，硕士Email：ting010151452@yahoo.com.cn
更新日期/Last Update: 2009-07-22