应用Tei指数与血浆BNP水平评价不稳定型心绞痛患者冠状动脉病变程度
《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]
- 期数:
- 2010年第1期
- 页码:
- 99-101
- 栏目:
- 临床研究
- 出版日期:
- 2010-01-04
文章信息/Info
- Title:
- Evaluation of coronary artery stenosis in patients with unstable angina by Tei index and brain natriuretic peptide
- 作者:
- 刘松岩1; 韩凤英2; 李毓忠1; 陈建权1; 聂新乾3
- 1.武警新疆总队医院急诊科，新疆 乌鲁木齐 830091；2.解放军474医院，新疆 乌鲁木齐 830010；3.新疆医科大学第二附属医院，新疆 乌鲁木齐 830028
- Author(s):
- LIU Song-yan1; HAN Feng-ying2; LI Yu-zhong1; CHEN Jian-quan1; NIE Xin-qian3
- 1.Department of Emergency Medicine, Xinjiang Municipal Corps Hospital, Chinese People’s Armed Police Forces, Ulumuqi 830091, Xinjiang, China; 2.No.474 Hospital of PLA, Urmuqi 830013, Xinjiang, China; 3.Second Affiliated Hospital of Xinjiang Medical Univer
- 分类号:
- R541.4
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 目的: 探讨多普勒超声心动图的Tei指数与血浆脑钠尿肽（BNP）浓度评估冠状动脉病变程度及心肌缺血的可能性。方法: 92例连续入选的不稳定型心绞痛（UAP）患者，30例疑似冠心病者作对照组，所有入选者均行冠状动脉造影（CAG）检查，按CAG结果将UAP患者分为单支病变组、双支病变组及三支病变组。记录Gensini积分，并进行超声心动图检查、血浆BNP浓度测定。结果: UAP患者组的Tei指数和血浆BNP浓度均显著增大或升高，且冠脉病变支数越多，Tei指数、BNP越大，且他们均是心肌缺血的独立预测指标。结论: Tei指数与BNP结合可用于评估冠状动脉病变程度，在筛选高危患者方面有一定意义。
- Abstract:
- AIM: To assess the value of Doppler echocardiographic Tei index and brain natriuretic peptide (BNP) in evaluating coronary artery stenosis in patients with unstable angina pectoris (UAP) and their relationship with myocardial ischemia. METHODS: Ninety two consecutive UAP patients and 30 controls with suspected coronary diseases were included in the study. All participants had previously undergone coronary angiography. According to the results, patients were divided into one-vessel disease group, two-vessel disease group and three-vessel disease group. Gensini scores were recorded, and echocardiography and cardiac hormonal analysis were performed. RESULTS: Tei index and BNP were higher in patients with UAP. They increased with the number of stenosed coronary arteries and were independent predictors of myocardial ischemia. CONCLUSIONS: A combination of Tei index and BNP is useful in evaluating the severity of coronary artery stenosis and screening high-risk patients for invasive management.
参考文献/References
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［2］ Yap LB, Ashrafian H, Mukerjee D. The natriuretic peptides and their role in disorders of right heart dysfunction and pulmonary hypertension［J］. Clinic Biochem, 2004, 37(10):847-857.
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［4］ Sahn DJ, DeMaria A, Kisslo J, et al. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements［J］. Circulation, 1978, 58(6):1072-1083.
［5］ Schiller NB, Shah PM, Crawford M, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms［J］. J Am Soc Echocardiogr, 1989, 2(5):358-367.
［6］ Khouri SJ, Maly GT, Suh DD, et al. A practical approach to the echocardiographic evaluation of diastolic function［J］. J Am Soc Echocardiogr, 2004, 17(3):290-297.
［7］ Tei C, Ling LH, Hodge DO, et al. New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function-a study in normals and dilated cardiomyopathy［J］. J Cardiol, 1995, 26(6):357-366.
［8］ Okawa M, Kitaoka H, Matsumura Y, et al. Functional assessment by myocardial performance index (Tei index) correlates with plasma brain natriuretic peptide concentration in patients with hypertrophic cardiomyopathy［J］. Circ J, 2005, 69(8):951-957.
备注/Memo
- 备注/Memo:
- 收稿日期：2008-12-18.作者简介:刘松岩,副主任医师Email:lsyone@126.com
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