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|本期目录/Table of Contents|

脑梗死患者隐匿性冠心病的相关因素

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2010年第3期
页码:
421-424
栏目:
临床研究
出版日期:
2010-04-06

文章信息/Info

Title:
Pathogenetic predictors of coronary artery disease in patients with cerebral infarction
作者:
刘松岩1; 韩凤英2; 李毓忠1; 聂新乾3
1.武警新疆总队医院急诊科, 新疆 乌鲁木齐 830091；2.解放军474医院妇产科, 新疆 乌鲁木齐830010;3.新疆医科大学第二附属医院急诊科，新疆 乌鲁木齐 830028
Author(s):
LIU Song-yan1;  HAN Feng-ying2;  LI Yu-zhong1;  NIE Xin-qian3
1.Department of Emergency Medicine, Xinjiang Municipal Corps Hospital, Chinese People’s Armed Police Forces, Urumuqi 830091, Xinjiang, China; 2.Department of Obstetrics and Gynaecology, PLA 474 Hospital, Urumqi 830010, Xinjiang, China; 3.Department of Emergency Medicine, Second Affiliated Hospital, Xinjiang Medical University, Urumqi 830028, Xinjiang, China
关键词:
脑梗死; 冠状动脉疾病; 代谢综合征; 血管造影; 磁共振成象
Keywords:
cerebral infarction;  coronary artery disease;  metabolic syndrome;  angiography;  magnetic resonance imaging
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的: 观察和分析脑梗死患者隐匿性冠心病的相关因素。方法: 104例脑梗死患者经冠状动脉造影和系统评价按是否患有隐匿性冠心病分组，观察临床特点，进行人体测量和影像学检查，分析冠心病的相关因素。结果: 39例(37.5%)患者患有冠心病,多元分析显示脑梗死患者并发的冠心病与代谢综合征(OR值5.01,95%CI:1.54-16.31;P<0.01)和颅内大动脉粥样硬化(OR值4.98, 95%CI:1.63-15.18;P<0.01)具有独立相关性。结论: 代谢综合征和颅内大动脉粥样硬化是脑梗死患者并发隐匿性冠心病的相关因素。
Abstract:
AIM: To estimate the prevalence of cardiovascular disease (CVD) in patients hospitalized for cerebral infarction and to determine the predictors of latent coronary heart disease (latent CHD). METHODS: One hundred and four patients with cerebral infarction without history of CVD underwent coronary angiography. Systematic evaluation was conducted on the basis of the presence of other vascular diseases, CVD risk factors and the degree of atherosclerosis. RESULTS: Thirty nine patients (37.5%) had CHD, 9(8.7%) had carotid artery stenosis, 9(8.7%) had peripheral artery disease of the lower limbs, and 3(2.9%) had atherosclerotic renal artery stenosis. Multiple regression analysis showed that the presence of CHD was independently associated with metabolic syndrome (OR 5.01, 95% CI 1.54-16.31; P<0.01) and intracranial large artery atherosclerosis (OR 4.98, 95% CI 1.63-15.18; P<0.01). CONCLUSION: Patients with cerebral infarction have a high prevalence of CVD, especially latent CHD. Both metabolic syndrome and intracranial large artery atherosclerosis may be potential predictors for identifying patients with cerebral infarction who are at the highest risk for latent CAD.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2009-04-20.作者简介：刘松岩，副主任医师Email:lsyone@126.com
更新日期/Last Update: 2010-04-09