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|本期目录/Table of Contents|

心房颤动的分子生物学机制研究进展

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2010年第3期
页码:
453-455
栏目:
综述
出版日期:
2010-04-06

文章信息/Info

Title:
-
作者:
刘佳顺12任澎2
1.新疆石河子大学医学院2006级研究生,新疆 石河子 832000; 2.新疆维吾尔自治区人民医院心内科,新疆 乌鲁木齐 830000
Author(s):
-
关键词:
心房颤动分子生物学机制基因治疗
Keywords:
-
分类号:
R541.75
DOI:
-
文献标识码:
A
摘要:
本文就心房颤动(AF)的基因表达及其改变,AF触发时基因的作用和AF的基因治疗作一综述。
Abstract:
-

参考文献/References

[1]周自强,胡大一,陈捷,等. 中国心房颤动现状的流行病学研究[J] . 中华内科杂志, 2004, 43(7):491-494.

[2]周微微,任卫东. 房颤发生机制研究进展[J]. 心脏杂志, 2003, 15(6):558-559,562.

[3] 杨阳,杨新莉. 心房颤动的易发因素及其机制研究[J]. 心脏杂志, 2005, 17(5):493-494.

[4] Darbar D, Herron KJ, Ballew JD, et al. Familial atrial fibrillation is a genetically heterogeneous disorder[J]. J Am Coll Cardiol, 2003, 41(12):2185-2192.

[5]Ellinor PT, Shin JT, Moore RK, et al. Locus for atrial fibrillation maps to chromosome 6q14-16[J].Circulation, 2003, 107(23):2880-2883.

[6]Chen YH, Xu SJ, Bendahhou S, et al. KCNQ1 gain-of-function mutation in familial atrial fibrillation[J]. Science, 2003, 29(5604)9:251-254.

[7]Yang Y, Xia M, Jin Q, et al. Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation[J]. Am J Hum Cenet, 2004, 75(5):899- 905.

[8]Zhang DF, Liang B, Lin J, et al. KCNE3 R53H substitution in familial atrial fibrillation[J]. Chin Med J(Engl), 2005, 118(20):1735-1738.

[9]Oberti C, Wang L, Li L, et al. Genome-wide linkage scan identifies a novel genetic locus on chromosome 5p13 for neonatal atrial fibrillation associated with sudden death and variable cardiomyopathy[J]. Circulation, 2004, 110(25):3753-3759.

[10]Lasse SR, Jacob HB, Ulrik D, et al. Relation of 97T polymorphism in KCNE5 to risk of atrial fibrillation[J]. Am J Cardiol, 2005, 96(3):405-407.

[11]Gaudino M, Andreotti F, Zamparelli R, et al. The-174G/C interleukin-6 polymorphism influences postoperative interleukin-6 levels and postoperative atrial fibrillation. Is atrial fibrillation an inflammatory complication[J]. Circulation, 2003, 108(Suppl 1): II195- II199.

[12]Firouzi M, Ramanna H, Kok B, et al. Association of human connexin 40 gene polymorphisms with atrial vulner-ability as a risk factor for idiopathic atrial fibrillation[J]. Circ Res, 2004, 95(4):e29-e33.

[13]Schreieck J, Dostal S, von Beckerath N, et al. C825Tpolymorphism of the G-protein beta3 subunit gene and atrial fibrillation: association of the TT genotype with a reduced risk for atrial fibrillation[J]. Am Heart J, 2004, 148(3):545-550.

[14]Watanabe H, Ma M, Washizuka T, et al. Thyroid hormone regulates mRNA expression and currents of ion channels in rat atrium[J]. Biochem BiophysRes Commun, 2003, 308(3):439-444.

[15]Kim YH, Lim DS, Lee JH, et al. Gene expression profiling of oxidative stress on atrial fibrillation in humans[J]. Exp Mol Med, 2003, 35(5):336-349.

备注/Memo

备注/Memo:
收稿日期:2008-03-12.通讯作者:任澎,主任医师,主要从事心电生理研究 Email:repengcvd@126.com 作者简介:刘佳顺,硕士生Email:hbs669125@yahoo.com.cn
更新日期/Last Update: 2010-04-09