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|本期目录/Table of Contents|

NADPH氧化酶与动脉粥样硬化

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2010年第5期
页码:
767-769
栏目:
综述
出版日期:
2010-06-22

文章信息/Info

Title:
-
作者:
权媛1; 2; 钱民章1
1.遵义医学院生物化学教研室，贵州 遵义 563003；2.上海中医药大学，上海 200032
Author(s):
-
关键词:
NADPH氧化酶; 动脉粥样硬化; 活性氧
Keywords:
-
分类号:
R543.5
DOI:
-
文献标识码:
A
摘要:
近年研究表明，烟酰胺腺嘌呤二核苷酸磷酸（NADPH）氧化酶是血管活性氧的主要来源。当活性氧的生成与清除平衡失调时，过多的活性氧可通过多种途径造成血管壁的损伤，成为致动脉粥样硬化（AS）的危险因素。在人和实验动物的AS病变部位，也发现NADPH氧化酶的活性与表达异常，NADPH氧化酶特异性抑制剂作为防治AS新的治疗靶标成为研究者们感兴趣的课题。
Abstract:
-

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2009-09-27.基金项目：贵州省科技厅基金项目资助(黔科合J字［2009］2178号) 通讯作者：钱民章，教授，主要从事动脉粥样硬化发病机理及天然产物防治的分子机制研究 Email:qian.mzh@hotmail.com 作者简介：权媛，博士生Email:QY81@yahoo.cn
更新日期/Last Update: 2010-06-22