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正常血压者不同血压水平的危险因素及其与相关疾病的关系

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2010年第6期
页码:
868-870
栏目:
临床研究
出版日期:
2010-08-23

文章信息/Info

Title:
Risk factors in subjects with normal blood pressure
作者:
杨文; 李燕玲
北京海军总医院干二科，北京100048
Author(s):
YANG Wen;  LI Yan-ling
Second Department of Geriatrics, Navy General Hospital, Beijing 100048, China
关键词:
血压; 危险因素
Keywords:
blood pressure;  risk factors
分类号:
R443.5
DOI:
-
文献标识码:
A
摘要:
目的: 观察正常血压者不同血压水平的危险因素及其与相关疾病的关系。方法： 对1 533例血压正常者按血压水平分为3组：血压<120/80 mmHg组，（120～129）/(80～84) mmHg组和（130～139）/（85～89） mmHg组。观察分析年龄、性别、体质量指数(BMI)、腰围、脉压差、血总胆固醇、三酰甘油、空腹血糖以及患冠心病、脑出血和脑梗死的情况与血压水平的关系。结果： 年龄、性别、BMI、腰围、脉压差、血总胆固醇、三酰甘油、空腹血糖和冠心病患病率在各血压组之间具有显著性差异（P<0.05，P<0.01）；多因素Linear regression分析发现年龄、BMI、腰围和三酰甘油是收缩压的相关因子（P<0.05，P<0.01），而只有腰围是舒张压的相关因子（P<0.01）。结论： 正常血压者随着血压水平的升高其心脑血管疾病的危险性也在逐渐增加，在预防血压升高的同时也要预防其危险因素的发生。
Abstract:
AIM：To explore the relationship between the levels of blood pressure and factors such as age, sex, body mass index (BMI), waist size, pulse pressure, total plasma cholesterol, plasma triglycerides, fasting blood glucose, incidence of coronary artery diseases, cerebral hemorrhage, and cerebral infarction in subjects with normal blood pressure. METHODS: Data such as age, sex, BMI, waist size, pulse pressure, total plasma cholesterol, plasma triglycerides, fasting blood glucose, incidence of coronary artery disease, cerebral hemorrhage and cerebral infarction were observed in a group of 1533 consecutive subjects with normal blood pressure. The relationship between these risk factors and blood pressure levels was studied. RESULTS: A significant difference was observed in age, sex, BMI, waist size, pulse pressure, fasting blood glucose, plasma triglycerides, incidence of coronary artery disease, cerebral hemorrhage and cerebral infarction between groups of different levels of blood pressure (P<0.05, P<0.01). With linear regression analysis, age, BMI, fasting blood glucose and plasma triglycerides were identified as significant and independent risk factors for systolic blood pressure (P<0.05, P<0.01) and only waist size was identified as a significant and independent risk factor for diastolic blood pressure (P<0.01). CONCLUSION: Risk factors for cardiovascular and cerebrovascular diseases increase with the level of blood pressure in subjects with normal blood pressure.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2009-12-03.作者简介：杨文，副主任医师，硕士Email:yangwen666123@sohu.com
更新日期/Last Update: 2010-08-22