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高血压病患者脉搏波传导速度与动态血压各指标的相关性分析

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2010年第6期
页码:
874-877
栏目:
临床研究
出版日期:
2010-08-23

文章信息/Info

Title:
Analysis of correlation between pulse wave velocity and indexes of ambulatory blood pressure in hypertensive patients
作者:
任春霖1; 陈志勇2; 胡胜利3
1.郧阳医学院附属东风总医院心内科，湖北 十堰 442008；2.湖北省十堰市房县中医院， 湖北 十堰 442100；3.福建医科大学附属第一医院神经外科,福建 福州 350004
Author(s):
REN Chun-lin1;  CHEN Zhi-yong2;  HU Sheng-li3
1.Department of Cardiology, Dongfeng General Hospital, Yunyang Medical College, Shiyan 442008, Hubei, China; 2.Department of Surgery, Hospital of Traditional Chinese Medicine of Fang County, Shiyan 442100, Hubei, China; 3.Department of Neurosurgery, First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, Fujian, China
关键词:
高血压病; 脉搏波传导速度; 动态血压
Keywords:
hypertension;  pulse wave velocity;  ambulatory blood pressure;  pulse pressure;  pulse pressure index
分类号:
R544.1
DOI:
-
文献标识码:
A
摘要:
目的: 探讨高血压病患者脉搏波传导速度（PWV）与动态血压（ABPM）各指标的相关性。方法: 对200例高血压病患者按年龄分为非老年高血压患者（年龄<60岁）和老年高血压患者（年龄≥60岁）两组；每组中再按PWV正常值分为<9 m/s和≥9 m/s两组。收集相关临床资料，测量身高、体质量、腰围、臀围，检测PWV和ABPM，计算24 h平均脉压（PP）、脉压指数（PPI）、体质量指数（BMI）、腰臀比（WHR），分析ABPM的各值及其他有关因素与PWV的相关性。结果: 与非老年高血压病患者比较：老年高血压病患者WHR、PP、PPI、PWV显著升高(P<0.05，P<0.01)；这两组中PWV≥9 m/s的患者，SBP、DBP、PP、PPI均高于同组内PWV<9 m/s的患者，组内比较有显著差异性（P<0.05，P<0.01)；经Pearson相关分析：PPI与 PWV 相关系数r值(0.501)大于SBP、DBP、PP的r值（0.398、-0.251、0.418）。结论: 高血压病患者PPI与PWV密切相关，在反映大动脉硬化程度上PPI优于动态血压其他指标。
Abstract:
AIM: To explore the correlation between pulse wave velocity (PWV) and indexes of ambulatory blood pressure (ABPM) in patients with hypertension. METHODS: A total of 200 patients with hypertension were divided into two groups: nonelderly (<60 years) group and elderly (≥60 years) group. In both groups, patients were subdivided into two groups: PWV<9 m/sec group and PWV≥9 m/sec group. Clinical data, PWV and indexes of ABPM were collected and the correlation between the indexes of ABPM, other relevant factors and PWV was analyzed. RESULTS: Compared with those in the nonelderly group, waist/hip ratio, pulse pressure (PP), pulse pressure index (PPI) and PWV in the elderly group were significantly higher (P<0.05 or P<0.01). Systolic blood pressure (SBP), diastolic blood pressure (DBP), PP and PPI of patients in PWV≥9 m/sec group were significantly higher than those in PWV <9 m/sec group in the same group (P<0.05 or P<0.01). Pearson correlation analysis showed that PPI was more closely correlated with PWV than with body mass index (BMI), PPI, PP, SBP and DBP. CONCLUSION: PWV is correlated with PP, SBP and DBP and significantly correlated with PPI in patients with hypertension.

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备注/Memo

备注/Memo:
收稿日期：2009-09-30.作者简介：任春霖,副主任医师Email: rcl640318@126.com
更新日期/Last Update: 2010-08-22