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|本期目录/Table of Contents|

高血压病患者静息心率和脉搏波速度、超敏C反应蛋白的关系(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2011年第3期
页码:
351-353
栏目:
临床研究
出版日期:
2011-05-12

文章信息/Info

Title:
Association of resting heart rate with pulse wave velocity and high-sensitivity C-reactive protein in hypertensive patients
作者:
李晓燕; 吴小庆; 郁志明; 陈茂华; 王华伟
无锡市人民医院心脏中心，江苏 无锡 214000
Author(s):
LI Xiao-yan;  WU Xiao-qing;  Yu Zhi-ming;  CHEN Mao-hua;  WANG Hua-wei
Heart Center , Wuxi Renmin Hospital, Wuxi 214000, Jiangsu, China
关键词:
高血压; 原发性; 静息心率; 脉搏波速度; 超敏C反应蛋白
Keywords:
hypertensive;  resting heart rate;  pulse wave velocity;  high-sensitivity C-reactive protein
分类号:
R544.1
DOI:
-
文献标识码:
A
摘要:
目的:探讨高血压病患者静息心率(RHR)与脉搏波速度（PWV）、超敏C反应蛋白（hs-CRP）的关系。方法： 入选高血压病患者278例，按RHR水平分为：RHR1组：<70 次/min，RHR2组：70～79次/min，RHR3组：≥80次/min。对入选患者测定颈－股脉搏波速度（PWV），并测空腹血糖(FPG)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、超敏C反应蛋白。结果： RHR3组的SBP、DBP均高于RHR1组、RHR2组；RHR2组SBP高于RHR1组；从RHR1组、RHR2组至RHR3组FBG、TC、TG、LDL-C、PWV、hs-CRP随着RHR的增加有增高的趋势（P<0.05或P<0.01），HDL-C随着RHR的增加有减少的趋势（P<0.05）。RHR与SBP、FBG、TC、TG、LDL-C、PWV、hs-CRP呈正相关(P<0.05或P<0.01)，与HDL-C呈负相关(P<0.05)。RHR2组或RHR3组的PWV、hs-CRP显著大于或高于RHR1组。结论： 高血压病患者RHR是PWV、hs-CRP、LDL-C的相关因素。
Abstract:
AIM:To study the relationship between resting heart rate (RHR) and pulse wave velocity (PWV) and high-sensitivity C-reactive protein (hs-CRP) in hypertensive patients. METHODS: Two hundred and seventy-eight hypertensive patients were enrolled in the study and, according to the RHR, were divided into three groups: group RHR 1 (<70/min, n=81), group RHR 2 (70-80/min, n=113) and group RHR 3 (>80/min, n=84). RHR, blood pressure, fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and PWV and hs-CRP were determined, and the correlation between RHR and the other parameters was analyzed. RESULTS: Both SBP and DBP in Group RHR3 are higher than in RHR1 or RHR2. SBP in Group RHR2 is higher than in Group RHR1. From Groups RHR1 and RHR2 to Group RHR3, RHP, FBG, TC, TG, LDL-C, PWV, and hs-CRP are prone to increase (P<0.05 or P<0.01), whereas HDL-C is prone to decrease (P<0.05). RHP is positively related to FBG, TC, TG, LDL-C, PWV, and hs-CRP (P<0.05 or P<0.01) and negatively related to HDL-C (P<0.05) PWV and hs-CRP in group RHR2 or group RHR3 were higher than those in RHR1. CONCLUSION: RHR is associated with PWV and hs-CRP in hypertensive patients.

参考文献/References

[1]Benetos AI.Hypertension-heart rate and cardiovascular risk[J].Arch Mal Vaiss,2000,93(11suppl):1371-1376.
[2]Gillman MW,Kannel WB,Belanger A,et al.Influence of heart rate on mortality among persons with hypertension:the Framingham Study[J].Am heart J,1993,125(4):1148-1154.
[3]中国高血压防治指南起草委员会.中国高血压防治指南(试行本)[J].高血压杂志,2000,8(1):94.
[4]Jamerson KA,Nesbitt SD,Amerena JV,et al.Angiotensin mediates forearm glucose uptake by hemodynamic rather than direct effects[J].Hypertension,1996,27(4):854-858.
[5]Palatini P,Julius S.The physiological determinants and risk correlations of elgvated heart rate[J].Am J Hypertens,1999,12(1pt 2):3S-8S.
[6]Rogowski O,Shapira I,Shirom A,et al.Heart rate and microinflammation in men: a relevant atherothrombotic link[J].Heart,2007,93(8):940-944.
[7]Carlberg B,Samuelsson O,Lindholm LH.Atenolol in hypertension:is it a wise choice?[J].Lancet,2004,364(9446):1684-1689.
[8]Shandelya SM, Kuppusarny P,Weisfeldt ML,et al.Evaluation of the role of polyrnorphonuclear leukoeytes on contractile function in myocardial reperfusion in jury evidence for plasmas mediated leuko cyte activation[J].Circulation,1993,87(2):536-546.
[9]张保国,王小迪,戴瑞美.不同年龄老年男性静息心率、血压、血脂水平的相关性[J].中国老年学杂志,2010,30(1):100-101.

备注/Memo

备注/Memo:
收稿日期：2010-03-21.作者简介：李晓燕，住院医生，硕士Email：shine198212142@126.com
更新日期/Last Update: 2011-03-17