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|本期目录/Table of Contents|

住院老年退行性心脏瓣膜病患者危险因素的分析(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2011年第5期
页码:
655-657
栏目:
临床研究
出版日期:
2011-10-25

文章信息/Info

Title:
Analysis of risk factors of senile degenerated valvular heart diseases
作者:
王翠英1; 李 敏1; 李虹伟2
首都医科大学附属北京友谊医院：1.医疗保健中心，2.心脏中心，北京 100050
Author(s):
WANG Cui-ying1;  LI Min1;  LI Hong-wei2
1.Medical and Health Center, 2.Heart Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
关键词:
瓣膜病; 心脏; 退行性; 钙化; 老年人
Keywords:
valvular diseases;  heart;  degenerative;  calcification;  senile
分类号:
R542.5
DOI:
-
文献标识码:
A
摘要:
目的:分析老年退行性心脏瓣膜病（SDHVD）患病的危险因素。方法： 回顾性分析52例老年SDHVD和68例无心脏瓣膜钙化的对照组的临床资料、超声心电图和其他辅助检查结果。对本研究涉及到的相关因素组间分布情况进行统计分析，并对存在组间差异的相关因素进行多因素的Logistic回归分析。结果： 单因素分析显示年龄、高血压病、冠心病、高脂血症在两组间分布有显著性差异。通过Logistic回归分析结果显示SDHVD的危险因素是年龄、高血压病和高脂血症。结论： 年龄、高血压病和高脂血症是SDHVD发病的危险因素。
Abstract:
AIM:To analyze the possible risk factors of senile degenerative valvular heart diseases (SDVHD). METHODS: Clinical data, cardiac ultrasound and other auxiliary examinations of 52 SDHVD patients and 68 patients without heart valvular calcification were analyzed retrospectively. Single factor statistical analysis of relevant factors between groups was conducted. A multifactorial logistic regression analysis between groups was conducted to identify the possible risk factors and their influence on the prevalence of SDVHD. RESULTS: Single factor statistical analysis showed significant differences in age, hypertension, coronary heart disease, and hyperlipidemia between groups. Multifactorial logistic regression analysis showed age, hypertension and hyperlipidemia were the possible risk factors for SDVHD. CONCLUSION: Risk factors for SDVHD include age, hypertension and hyperlipidemia.

参考文献/References

[1]Ing SW,Mohler Iii ER,Putt ME,et al.Correlates of valvular ossification in patients with aortic valve stenosis[J].Clin Transl Sci,2009,2(6):431-435.

[2]刘立新,赵玉生,武云涛,等.老年钙化性心脏瓣膜病临床分析[J].中华老年多器官疾病杂志,2010,9(1):23-26.

[3]Peltonen T, N?p?nkanga J, Vuolteenaho O,et al.Apelin and its receptor APJ in human aortic valve stenosis[J].J Heart Valve Dis, 2009,18(6):644-652.

[4]张 涛,朱思平,陆小伟,等.老年退行性心瓣膜病变与颈动脉粥样硬化相关性分析[J].实用老年医学,2006,20(6):390-392.

[5]Togashi M,Tamura K,Masuda Y,et al.Comparative study of calcified changes in aortic valvular diseases[J].J Nippon Med Sch,2008,75(3):138-145.

[6]Filsoufi F,Rahmanian PB,Castillo JG,et al.Incidence, imaging analysis, and early and late outcomes of stroke after cardiac valve operation[J].Am J Cardiol,2008,101(10):1472-1478.

[7]K?se N,Ayta oglu BN,Yilmaz N,et al.Citric acid as a decalcifying agent for the excised calcified human heart valves[J].Anadolu Kardiyol Derg,2008,8(2):94-98.

[8]Malyar NM,Schlosser T,Buck T,et al.Using cardiac magnetic resonance tomography for assessment of aortic valve area in aortic valve stenosis[J].Herz,2006,31(7):650-657.

备注/Memo

备注/Memo:
收稿日期：2010-12-12.基金项目：中华医学会临床医学科研专项基金资助（09010100165） 作者简介：王翠英，副主任医师，硕士Email: ccmucpmu@yahoo.cn
更新日期/Last Update: 2011-11-03