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|本期目录/Table of Contents|

青年急性冠脉综合征的危险因素(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2011年第5期
页码:
661-663
栏目:
临床研究
出版日期:
2011-10-25

文章信息/Info

Title:
Risk factors for young patients with acute coronary syndrome
作者:
何 华; 韩福生; 贾 平; 刘 巍; 崔 松; 马临安
首都医科大学附属北京安贞医院急诊心内科，北京 100029
Author(s):
HE Hua;  HAN Fu-sheng;  JIA Ping;  LIU Wei;  CUI Song;  MA Lin-an
Department of Emergency Cardiology, Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing 100029, China
关键词:
青年; 急性冠脉综合征; 危险因素; 睡眠缺乏
Keywords:
young patients;  acute coronary syndrome;  risk factor;  sleep deprivation
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的: 通过病例对照研究探讨35岁以下青年急性冠脉综合征（ACS）的危险因素。方法： 选择我院就诊的18～35岁急性心肌梗死和不稳定型心绞痛患者作为ACS组，同期就诊、年龄和性别匹配的非ACS患者作为对照组，记录两组的临床特征，包括年龄、性别、体质量指数（BMI）、吸烟史、饮酒史、是否并发高血压病、糖尿病和血脂异常、ACS类型、冠脉病变情况，然后通过单因素和多因素分析判断青年ACS的危险因素。结果： 两组各入选338例患者，单因素分析表明ACS组吸烟、高血压病、糖尿病、血脂异常、肥胖、睡眠缺乏者显著高于非ACS组，进一步多因素分析表明吸烟、高血压病、糖尿病、血脂异常、肥胖、睡眠缺乏是青年ACS发病的独立危险因素，诱发青年ACS的OR值分别是2.0、2.3、2.9、2.4、3.2和1.5。结论： 本研究表明除吸烟、高血压病、糖尿病、血脂异常、肥胖等因素外，睡眠缺乏也是35岁以下青年ACS患者的独立危险因素。
Abstract:
AIM:To probe into the risk factors for acute coronary syndrome (ACS) in patients <35 years old. METHODS: ACS in patients aged 18-35 years old from January 2005 to August 2010 were selected as case group. Age- and gender-matched non-ACS patients treated at our hospital during the same period were selected as the control group. Clinical characteristics in the two groups were investigated and recorded, and single-factor analysis and multivariate analysis were performed to analyze the risk factors for ACS in patients <35 years old. RESULTS: There were 338 included cases in each group. Single-factor analysis indicated that the number of patients with smoking, concomitant essential hypertension, diabetes mellitus, dyslipidemia, increased BMI, and sleep deprivation in the ACS group was higher than in the non-ACS group, and the multivariate analysis indicated that the above-mentioned factors were independent risk factors for ACS in patients <35 years old, with OR values, respectively, 2.0, 2.3, 2.9, 2.4, 3.2 and 1.5. CONCLUSION: In addition to smoking, concomitant essential hypertension, diabetes mellitus, dyslipidemia, and increased BMI along with sleep deprivation are also independent risk factors for ACS in patients <35 years old.

参考文献/References

[1]中华医学会心血管病学分会,中华心血管病杂志编辑委员会,中国循环杂志编辑委员会.急性心肌梗死诊断和治疗指南[J].中华心血管病杂志，2001,29(12):705-720.

[2]Braunwald E,Antman EM,Beasley JW,et al.ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction--summary article: a report of the American College of Cardiology/American Heart Association task force on practice guidelines (Committee on the Management of Patients with Unstable Angina)[J].J Am Coll Cardiol,2002,40(7):1366-1374.

[3]World Health Organization.Guidelines for controlling and monitoring the tobacco epidemic[R].Geneva: World Health Organization,1998.

[4]Chen MJ,Chiou YY,Wu DC,et al.Lifestyle habits and gastric cancer in a hospital-based case-control study in Taiwan[J].Am J Gastroenterol,2000,95(11):3242-3249.

[5]中华人民共和国卫生部,卫生部心血管病防治研究中心,高血压联盟（中国）中国高血压防治指南修订委员会.中国高血压防治指南2005年修订版[M].北京:人民卫生出版社.

[6]卫生部疾病控制司,中华医学会糖尿病学分会.中国糖尿病防治指南[J].中国慢性病预防与控制，2004，12(6):283-286.

[7]中华心血管病学会,中华心血管病杂志编委会,血脂异常防治对策专题组.血脂异常防治建议（第一版）[J].中华心血管病杂志，1997，25(2):169-175.

[8]Orzel-Gryglewska J.Consequences of sleep deprivation[J].Int J Occup Med Environ Health,2010,23(1):95-114.

[9]Yang W,Lu J,Weng J,et al.China National Diabetes and Metabolic Disorders Study Group Collaborators. Prevalence of diabetes among men and women in China[J].N Engl J Med,2010,362(12):1090-1101.

[10]卫生部心血管病防治研究中心.中国心血管病报告2005[M].北京：中国大百科全书出版社，2006.

[11]王劲松,余金明,胡大一,等.北京城乡社区20~44岁居民高血压患病率及其危险因素[J].中华高血压杂志,2009,(9): 716-718.

[12]Bjorvatn B,Sagen IM,Oyane N,et al.The association between sleep duration,body mass index and metabolic measures in the Hordaland Health Study[J].J Sleep Res,2007,16(1):66-76.

[13]Chaput JP,Després JP,Bouchard C,et al.The association between sleep duration and weight gain in adults:a 6-year prospective study from the Quebec family study[J].Sleep,2008,31(4):517-523.

[14]Gottlieb DJ,Redline S,Nieto FJ,et al.Association of usual sleep duration with hypertension:the Sleep Heart Health Study[J].Sleep,2006，29（8）:1009-1014.

[15]Gottlieb DJ,Punjabi NM,Newman AB,et al.Association of sleep time with diabetes mellitus and impaired glucose tolerance[J].Arch Intern Med,2005,165（8）:863-867.

备注/Memo

备注/Memo:
收稿日期：2010-12-25.作者简介：何华，主治医师，博士Email：hehua430@163.com
更新日期/Last Update: 2011-11-03