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Title:: Assessment of left ventricular function by two-dimensional strain imaging in patients with different-stage chronic renal disease

作者:: 张丽¹; 林萍¹; 于妍洁¹; 赵久阳²; (大连医科大学附属第二医院:1.超声科,2.肾内科，辽宁大连 116027)

Author(s):: ZHANG Li¹; LIN Ping¹; YU Yan-jie¹; ZHAO Jiu-yang²; (1.Department of Ultrasound, 2.Department of Nephrology, Second Affiliated Hospital of Dalian Medical University, Dalian 116027, Liaoning, China)

关键词:: 二维应变; 慢性肾脏病; 左室功能

Keywords:: two-dimensional strain; chronic renal diseases; left ventricular function

分类号:: R445.1

DOI:: -

文献标识码:: A

摘要:: 目的:探讨二维应变技术（2DS）评价不同分期慢性肾脏病患者左室收缩功能的价值。方法：100名慢性肾脏病患者按肾小球滤过率分为3组，A组（n=30）、B组（n=30）及C组（n=40），同时选取30名健康志愿者为正常对照组，分别取二维条件下心尖四腔切面、心尖两腔切面、心尖长轴切面3个连续心动周期图像。应用2DS获取左室18个节段心肌应变(s)及舒张早期应变率（SRe），并计算整体应变（GLS）。结果：A组左室壁部分节段应变、应变率低于正常组。B组除间隔心尖段、下壁基底段、中间段以外，其余各节段收缩期应变均低于正常组， B组、C组各节段舒张早期应变率均低于正常组。其中，C组除前壁中间段、后壁心尖段以外，其他节段均较A组降低。B组、C组整体应变低于正常。结论：二维应变技术可以早期发现慢性肾脏病患者左室心肌收缩及舒张功能的异常。

Abstract:: AIM:To evaluate the application of two-dimensional strain imaging (2DS) in assessing the left ventricular function in patients with chronic renal diseases. METHODS: One hundred patients with chronic renal diseases were divided into three groups: group A (n=30), group B (n=30) and group C (n=40) according to the severity of the renal disease and underwent 2DS. Thirty two healthy subjects were recruited as control group. Four-chamber apical views, two-chamber apical views and left ventricular long-axis views of two-dimensional images were stored. Longitudinal strain (S) and early diastolic strain rate (SRe) of left ventricular segments were obtained by 2DS software. RESULTS: Compared with those in the control group, the S and SRe in some segments in group A decreased and except for the S of the apical anteroseptum and the basal and middle segments of inferior wall, the S and SRe of each wall of left ventricle in group B also decreased. The S and SRe of all segments in group C significantly decreased compared with those in the control group. Except for the cardiac middle segment of anterior wall and the cardiac apex of inferior wall, the SRe of each wall of the left ventricle in group C decreased compared with those in group A. Global longitudinal peak systolic strain (GLS) in group B and group C significantly decreased compared with that in the control group. CONCLUSION: Two-dimensional strain imaging can detect early left ventricular dysfunction in patients with chronic renal diseases.

参考文献/References

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二维应变技术对不同分期慢性肾脏病患者左室功能的评价(PDF)

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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