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|本期目录/Table of Contents|

锌指蛋白36家族的研究进展

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2013年第2期
页码:
238-240
栏目:
综述
出版日期:
2013-04-25

文章信息/Info

Title:
Research progress of zinc finger protein 36
作者:
努尔布维·吐尔孙; 姚晓光 综述; 李南方 审校
(新疆维吾尔族自治区人民医院高血压病科、新疆高血压病诊断治疗研究中心，新疆 乌鲁木齐 830001)
Author(s):
Nuerbuwei·Tuersun;  YAO Xiao-guang;  LI Nan-fang
(Center of Hypertension, People’s Hospital of Xinjiang Uygur Autonomous Region & Xinjiang Hypertension Institute, Urumqi 830001, Xinjiang, China)
关键词:
锌指蛋白36; 转录后调节因子; 候选基因
Keywords:
zinc finger protein 36;  transcriptional regulatory factor;  candidate gene
分类号:
Q51
DOI:
-
文献标识码:
A
摘要:
本文对锌指蛋白（ZFP）36家族成员的结构和功能的研究进展进行了综述。研究表明，ZFP36作为转录后调节因子，参与了多种生物学功能包括炎症、代谢综合征及肿瘤的发生发展，并证明ZFP36基因可作为肥胖相关的代谢综合征的重要候选基因。
Abstract:
Research on family members and structure and function of zinc finger protein 36 (ZFP36) was reviewed. Studies have shown that ZFP36 as a post-transcriptional regulatory factor is involved in a variety of biological functions including the development of its important role in inflammation, metabolic syndrome and tumorigenesis, and that ZFP36 gene is an important candidate gene for obesity-related metabolic syndrome.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2012-03-15.基金项目：国家级重点临床专科资金项目资助 通讯作者：李南方，主任医师，主要从事高血压病的临床分子生物学及流行病学研究 Email:lnanfang@yahoo.com.cn 作者简介：努尔布维·吐尔孙，住院医师，硕士 Email:nurbuvy@hotmail.com
更新日期/Last Update: 2013-04-28