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抽吸导管联合硝普钠在急性心肌梗死介入治疗中的作用

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2013年第4期
页码:
447-449453
栏目:
临床研究
出版日期:
2013-07-25

文章信息/Info

Title:
Effect of aspiration catheter and sodium nitroprusside on treatment for patients with acute myocardial infarction treated by primary percutaneous coronary intervention
作者:
徐晓辉1; 武卫党1; 王聪霞2; 路 艳1; 丁法明2
(1.西电集团医院心内科，陕西 西安710077；2.西安交通大学医学院第二附属医院心内科，陕西 西安 710004)
Author(s):
XU Xiaohui1;  WU Weidang1;  WANG Congxia2;  LU Yan1;  DING Faming2
(1.Department of Cardiovasology, Xidian Group Hospital, Xi’an 710077, Shaanxi, China; 2.Department of Cardiovasology, Second Affiliated Hospital, Medical School, Xi’an Jiaotong University, Xi’an 710004, Shaanxi, China)
关键词:
抽吸导管; 硝普钠; 心肌梗死; 急性; ST段抬高型; 经皮冠状动脉介入治疗
Keywords:
aspiration catheter;  sodium nitroprusside;  acute STelevation myocardial infarction;  percutaneous coronary intervention
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的:探讨在急性ST段抬高型心肌梗死(STEMI)患者经皮冠状动脉介入（PCI）治疗中应用抽吸导管联合冠脉内注射硝普钠对改善心肌组织灌注及预后的影响。方法:146例于我院行急诊PCI的STEMI患者，分为常规PCI组（常规治疗组）、抽吸导管组（导管抽吸组）、抽吸导管联合硝普钠组（联合措施组），比较3组术后TIMI血流恢复情况及术后30 d主要不良心血管事件(major adverse cardiac events,MACE)的发生率。结果:单纯使用抽吸导管组及抽吸导管联合硝普钠组与常规PCI组相比均能明显改善STEMI患者术后TIMI血流及预后（P<0.05），抽吸导管联合硝普钠组与单纯抽吸导管组相比能进一步改善STEMI患者术后TIMI血流（P<0.05）,且能明显减少术后MACE事件的发生率。结论:抽吸导管联合硝普钠可进一步改善心肌梗死患者冠脉血流状态，同时有可降低术后MACE发生率的趋势，尚须大样本证实。
Abstract:
AIM:To investigate the effects of aspiration catheter and sodium nitroprusside on myocardial reperfusion for treatment of patients with acute STelevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PCI). METHODS: One hundred and fortysix patients with STEMI who underwent primary PCI were divided into three groups: 56 patients routinely treated without aspiration catheter (control group), 44 patients treated with aspiration catheter (group A), and 46 patients treated with aspiration catheter and sodium nitroprusside (group B). Patients were followedup prospectively for the incidence of major adverse cardiac events (MACE) including death, reinfarction and revascularization. RESULTS: The slowreflow phenomenon and MACE were much less in both group A and group B, especially in group B (P<005). CONCLUSION: Application of aspiration catheter and sodium nitroprusside improves coronary flow and lowers the incidence of MACE.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2012-12-26.作者简介：徐晓辉，副主任医师 Email：xuxh5555@163.com
更新日期/Last Update: 2013-07-29