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Title:: Survey of calmodulin and sympathetic nerve changes based on heart and channel acupoints

作者:: 嵇波; 胡琅琳; 李志刚; 张露芬; 李晓泓; 许咏思; 张鹤; (北京中医药大学针灸推拿学院综合实验室，北京 100029)

Author(s):: JI Bo; HU Langlin; LI Zhi gang; ZHANG Lu fen; LI Xiao hong; XU Yong si; ZHANG He; (Integrated Laboratory of Acupuncture Moxibustion and Tuina School, Beijing University of Chinese Medicine, Beijing 100029)

关键词:: 钙调蛋白; 交感神经; 经穴脏腑相关; 心血管

Keywords:: calmodulin; sympathetic nerves; channel acupoints; zangfu organs; cardiac vessels

分类号:: R224

DOI:: -

文献标识码:: A

摘要:: Ca2+、钙调蛋白(calmodulin,CaM)和交感神经(sympathetic nerves，SN)在心血管系统生理病理变化及经脉穴位的效应中发挥着重要作用。本文系统分析了Ca2+CaM在心肌功能活动中和心肌缺血中的效应，在药物干预心血管功能活动中的介导效应及其介导的经穴-脏腑相关的效应；SN在经穴-脏腑相关中的介导效应，在心血管生理功能和病理变化中的效应，CaM与SN的相关性以及二者在心脏、经脉穴位效应中的可能机制。发现Ca2+CaM和SN与心脏、经脉穴位密切相关。目前很少有人关注Ca2+CaM和SN在心脏与经脉穴位相关过程中的变化规律和机制。因此，基于Ca2+CaM和SN探讨心脏-经脉经穴相关的双向效应和机制，将会为经络的理论研究提供一个新的思路，值得深入探讨。

Abstract:: Ca2+, calmodulin (CaM) and sympathetic nerves (SN) play an important role on the pathophysiological changes of the vascular system and the effect of acupoints. By systematically analyzing the effect of Ca2+CaM on myocardial activity and on ischemia, the conductive effect of Ca2+CaM on drugs that intervene in cardiovascular functions of Ca2+CaM and SN on the correlation between the channel points and zangfu organs, intervention of SN on the correlation between the channel points and zangfu organs, the effect of SN on the pathophysiological changes of the vascular system, correlation between CaM and sympathetic nerves, mechanism of Ca2+CaM and sympathetic nerves in the effect of heart and channel acupoints, it has been found that Ca2+CaM and the sympathetic nerves are closely related to the heart and channel acupoints. At present, few people pay close attention to the mechanisms of Ca2+CaM and SN in the correlation between the heart and acupoints. Therefore, our survey of the correlation between the heart and acupoints based on calmodulin and sympathetic nerves will open a new perspective for theoretical research. It is worthwhile to further investigate into channel points.

参考文献/References

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基于心脏和经脉穴位探讨Ca2+-钙调蛋白与交感神经变化的研究

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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