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|本期目录/Table of Contents|

高糖诱导血管内皮细胞损伤的调控机制研究进展

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2013年第5期
页码:
609-612
栏目:
综述
出版日期:
2013-09-25

文章信息/Info

Title:
Regulation mechanisms of high glucoseinduced vascular endothelial cell injury
作者:
谢玉凤; 杨胜利; 刘惠亮
(武警总医院心内科，北京 100039)
Author(s):
XIE Yu feng;  YANG Sheng li;  LIU Hui liang
(Department of Cardiology, General Hospital, Armed Police Forces, Beijing 100039, China)
关键词:
高糖; 内皮细胞; 调控机制
Keywords:
high glucose;  vascular endothelial cells;  regulation mechanism
分类号:
R543
DOI:
-
文献标识码:
A
摘要:
目前关于高糖诱导血管内皮细胞损伤的机制有多种，包括非酶促糖基化终产物的积聚、二酰甘油/蛋白激酶C通路的激活及氧化应激的增强等。这些途径都是被高糖激活的，彼此之间又能相互作用。
Abstract:
Various mechanisms have been proposed explaining how high glucose induces vascular endothelial cell injury, such as the accumulation of advanced glycation endproducts, activated diacylglycerol/protein kinase C pathway, and increased oxidative stress. These pathways are all activated through hyperglycemia and their actions potentiate each other.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2013-03-21.通讯作者：刘惠亮，主任医师，主要从事心血管介入研究 Email:huiliangl531@163.com 作者简介：谢玉凤，硕士生 Email:xyf_1117@126.com
更新日期/Last Update: 2013-09-30