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Title:: Research progress of bone marrow mesenchymal stem cells in the repair of myocardial injury

作者:: 沈利水¹综述; 屈百鸣²审校; （1.浙江中医药大学第二临床医学院，浙江杭州 310014；2.浙江省人民医院心内科，浙江杭州 310014）

Author(s):: SHEN Li shui¹; QU Bai ming²; （1.Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, China; 2.Department of Cardiology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, Zhejiang, China）

关键词:: 骨髓间充质干细胞; 心肌梗死; 损伤; 修复

Keywords:: bone marrow mesenchymal stem cells; myocardial infarction; injury; repair

分类号:: R542.2

DOI:: -

文献标识码:: A

摘要:: 心肌梗死（MI）具有较高的死亡率，大面积MI后幸存的患者，常因心肌结构重构而逐渐发展为心力衰竭，预后往往欠佳。近来研究发现，骨髓间充质干细胞(bone marrow mesenchymal stem cells，BMSCs)作为多潜能干细胞，对受损的心肌具有积极的修复作用，为改善MI患者的预后提供了一个新途径。本文主要就BMSCs修复受损心肌的相关机制作一综述。

Abstract:: Myocardial infarction (MI) has a high mortality. Survival of MI in patients usually gradually develops into heart failure due to myocardial remodeling. The prognosis is poor. Recent studies have shown that bone marrow mesenchymal stem cells (BMSCs), a type of pluripotent stem cells, have a positive effect on the damaged myocardium, which provides a therapeutic alternative for improving the prognosis of MI patients. This article mainly reviews the mechanism of BMSCs in cardiac repair.

参考文献/References

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骨髓间充质干细胞修复心肌损伤的研究进展

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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