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Title:: Effect of aldosterone level on the prognosis of acute myocardial infarction

作者:: 孙云飞; 郎济艳; (黑龙江省森工总院、黑龙江省红十字医院心内科，黑龙江哈尔滨 150040)

Author(s):: SUN Yun fei; LANG Ji yan; (Departmen of Cardiology, Heilongjiang Forestry General Hospital, Heilongjiang Red Cross Hospital, Harbin 150040, Heilongjiang, China)

关键词:: 醛固酮; 急性心肌梗死; 预后

Keywords:: aldosterone; myocardial infarction; prognosis

分类号:: R541.4

DOI:: -

文献标识码:: A

摘要:: 目的:探讨发病初期醛固酮水平对急性心肌梗死（AMI）预后的影响。方法:选取资料完整的AMI患者160例，进行分析。按入院时醛固酮水平分为3组：最低值组（<123.4 pmol/L），中值组（123.4~160.3 pmol/L）和高值组（>160.3 pmol/L）。比较各组心肌酶水平，心功能指标，室性心律失常发生率，住院及3年病死率。结果:①3组间住院病死率和3年病死率分别为低值组：4%，8%，中值组：5%，12%，高值组：12%，32%，高值组3年病死率与中低值组比较均有统计学意义（P<0.01）。②3组间肌酸激酶（CK）、肌酸激酶同工酶（CK-MB）及左室射血分数（LVEF）值，高值组分别与中低值组之间进行比较，差异有统计学意义(P<0.05)。结论:AMI初期时高醛固酮水平患者的预后较差。

Abstract:: AIM:To investigate the effect of aldosterone level in early onset on the prognosis of acute myocardial infarction (AMI). METHODS: Data of AMI patients were analyzed in 160 cases (male 118 cases, female 42 cases). According to the aldosterone levels, patients were divided into three groups: minimum value group (<123.4 pmol/L), median value group (123.4-160.3 pmol/L) and high value group (>160.3 pmol/L). The levels of myocardial enzyme, cardiac function index, incidence of ventricular arrhythmias and inhospital and 3year mortality rates were compared. RESULTS: Inhospital and 3-year mortality rate of minimum value group, medium value group and high value group were, respectively, 3.8% & 11.6%, 7.7% & 12.3%, and 4.6% & 31.9%, and those in high value group were significantly different from those in minimum value group and medium value group (P<0.01). Creatine kinase (CK) and creatine kinase MB isoenzyme (CK-MB), left ventricular ejection fraction (EF) and incidence of ventricular arrhythmia in the high value group were significantly different, respectively, from those in minimum value group and medium value group (P<0.05). CONCLUSION: High aldosterone levels at early onset exert a significant effect on the prognosis of AMI.

参考文献/References

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醛固酮水平对急性心肌梗死预后的影响

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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