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|本期目录/Table of Contents|

高血压病患者动态血压参数与左心室舒张功能相关

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2015年第1期
页码:
38-040
栏目:
临床研究
出版日期:
2014-09-25

文章信息/Info

Title:
Association between ambulatory blood pressure and left ventricular diastolic functions in patients with hypertension
作者:
尼罗帕; 布娃加·吾守尔; 姜淑霞
(新疆医科大学第一附属医院干部病房内二科，新疆 乌鲁木齐 830054)
Author(s):
NI Luo-pa;  BUWAJIA Wushouer;  JIANG Shu-xia
(Second Department of Cardiology, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, Xinjiang, China)
关键词:
高血压; 原发性; 动态血压参数; 左心室舒张功能
Keywords:
essential hypertension;  blood pressure;  ambulatory;  left ventricular diastolic function
分类号:
R544
DOI:
-
文献标识码:
A
摘要:
目的:探讨高血压病患者动态血压参数与左心室舒张功能的相关性。方法: 入选原发性高血压患者137例，询问病史、体检并采用超声心动图测收缩末期左、右心房内径、左心室舒张末期内径（LVEDD）、左心室射血分数（LVEF）。左心室舒张功能测定用二尖瓣舒张早期血流峰值速度/舒张晚期血流峰值速度（E/A）值，以评价左室舒张功能。根据E/A值的大小将原发性高血压患者分为两组，E/A≥1组视为左心室舒张功能正常组（n=54例），E/A<1为左心室舒张功能不全组（n=83例）。患者均行24h动态血压及血生化检测。结果: (1)左心室舒张功能不全组的24h平均收缩压(24hSBP)、LVEDD明显高于功能正常组，差异有统计学意义(P<0.05)。（2）偏相关性分析显示左室舒张功能与LVEDD、24hSBP呈显著正相关（r值分别为0.70,0.40,P<0.01）。结论: 高血压病患者动态血压参数与左心室舒张功能相关。
Abstract:
AIM:To investigate the relationship between different parameters of blood pressure and left ventricular diastolic function in patients with hypertension. METHODS: The study was performed in 137 patients with hypertension who were questioned for clinical history and given a physical examination, ambulatory blood pressure monitoring, echocardiography, and blood biochemistry detection. Inner diameters of left and right atriums during end-systolic period, left ventricular diameter of end diastolic period, and ejection fraction (E/A) were measured by echocardiography to analyze left ventricular diastolic functions. E/A fraction was used to evaluate the left ventricular diastolic function. Patients were divided into two groups according to their E/A fraction: normal left ventricular function group with E/A≥1 (n=54) and abnormal left ventricular function group with E/A <1 (n=83). Ambulatory blood pressure was measured and blood biochemistry detection was conducted. Correlation between left ventricular diastolic function and parameter changes of patients' 24-h blood pressure was analyzed using χ2 test. RESULTS: Twenty-four-hour systolic blood pressure and left ventricular diameter of end diastolic period in the abnormal left ventricular function group was significantly higher than in the normal left ventricular function group (P<0.05). Partial correlation analysis showed a positive correlation between left ventricular function and LVEDD and 24-h SBP (r=0.70, 0.40, P<0.01). CONCLUSION: Left ventricular diastolic function is positively related to the 24-h systolic blood pressure in patients with essential hypertension.

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备注/Memo

备注/Memo:
收稿日期：2014-02-21.
通讯作者：布娃加·吾守尔，主任医师,主要从事心血管疾病研究Email：bwj4365@sina.com
作者简介：尼罗帕，硕士生Email:niluopa@126.com
更新日期/Last Update: 2015-01-20