我们的网站为什么显示成这样？

可能因为您的浏览器不支持样式，您可以更新您的浏览器到最新版本，以获取对此功能的支持，访问下面的网站，获取关于浏览器的信息：

|本期目录/Table of Contents|

下体负压晕厥时人体心血管反应特征

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2015年第1期
页码:
51-054
栏目:
临床研究
出版日期:
2014-09-25

文章信息/Info

Title:
Cardiovascular response to syncope induced by lower body negative pressure
作者:
吕云利1; 高 原2; 杨长斌2; 王永春2; 赵 波1; 孙喜庆2
(1.兰州军区总医院安宁分院神经内科，甘肃 兰州 730070；
2.第四军医大学航空航天医学系 航空航天生物动力学教研室，航空航天医学教育部重点实验室，陕西 西安 710032)
Author(s):
LV Yun-li1;  GAO Yuan2;  YANG Chang-bin2;  WANG Yong-chun2;  ZHAO Bo1;  SUN Xi-qing2
(1.Department of Neurology, Anning Branch, General Hospital, Lanzhou Military Area Command, Lanzhou 730070, Gansu, China;
2.Department of Aerospace Biodynamics & MOE Key Laboratory of Aerospace Medicine, School of Aerospace Medicine, Fourth Military Medical University, Xi’an 710032, China)
关键词:
心血管功能; 下体负压; 耐力;  每搏量
Keywords:
cardiovascular function;  lower body negative pressure;  tolerance;  stroke volume
分类号:
R54
DOI:
-
文献标识码:
A
摘要:
目的:分析下体负压诱发晕厥时人体心血管反应的变化特征，为确立意识丧失预警生理参数提供科学依据。方法: 10名健康男性被试者进行梯度下体负压暴露至晕厥前状态，同时连续观察血压、心率、心脏泵血功能及自主神经功能的变化。结果: 在下体负压暴露时，被试者下体负压耐力平均为（856±95） s。下体负压耐力终点前60 s和30 s时被试者心率较基础值分别增加41%和45%（P<0.05），每搏量分别降低49%和49%（P<0.01）；耐力终点时心率增加63%（P<0.05）,每搏量降低50%（P<0.01）。下体负压耐力终点前收缩压显著降低（P<0.05），低频功率/高频功能(LH/HF)显著升高（P<0.05）。结论: 心率和每搏量的变化量可作为监测意识状态的重要参考指标。
Abstract:
AIM:To analyze the changes of cardiovascular response to syncope induced by lower body negative pressure (LBNP) in humans. METHODS: Ten healthy male subjects were exposed to LBNP until pre-syncope. Blood pressure, heart rate (HR), cardiac pumping function and autonomic regulation were examined during LBNP. RESULTS: Mean duration of lower body negative pressure was (856±95) s. Heart rate (HR) increased significantly by 41% and 45%, whereas stroke volume (SV) decreased by 49% and 49%, respectively at 60 s and 30 s before end-point of LBNP as compared with baseline. HR increased by 63%, whereas SV decreased by 50% at the end-point of LBNP. Systolic blood pressure was significantly lower, whereas the ratio of low frequency power/high frequency power was significantly higher before the end-point of LBNP as compared with baseline. CONCLUSION: Changes of stroke volume and heart rate may be an important index for consciousness monitoring.

参考文献/References

[1]孙喜庆,李莹辉,姜世忠.重力生理学理论与实践[M].西安:第四军医大学出版社,2009.
[2]Whinnery JE,Glaister DH,Burton RR.+Gz-induced loss of consciousness and aircraft recovery[J].Aviat Space Environ Med,1987,58(6):600-603.
[3]Albery WB,Van Patten RE.Non-invasive sensing systems for acceleration-induced physiologic changes[J].IEEE Eng Med Biol Mag,1991,10(1):46-51.
[4]Cammarota JP.Integrated systems for detecting and managing acceleration-induced loss of consciousness[J].IEEE Eng Med Biol Mag,1991,10(1):52-55.
[5]Arbeille P,Becker F,Thiney G,et al.Effect of the elastic compression stockings on the calf veins and tissues during a simulated orthostatic test(LBNP)[J].J Gravit Physiol,2007,14(1):59-60.
[6]杨长斌,孙喜庆.下体负压的研究进展[J].中华航空航天医学杂志,2002,13(2):107.
[7]徐 莉,杨长斌,周林甫,等.下体负压联合体能训练对心脏功能及自主神经调节的影响[J].心脏杂志,2010(6):928-933.
[8]Lightfoot JT,Hilton F Jr,Fortney SM.Repeatability and protocol comparability of presyncopal symptom limited lower body negative pressure[J].Aviat Space Environ Med,1991,62(1):19-25.
[9]耿喜臣,陈立君,颜桂定,等.新型抗荷系统抗荷性能的离心机评价[J].中华航空航天医学杂志,2005,16(4):241-244.
[10]Smit AA,Wieling W,Fujimura J,et al.Use of lower abdominal compression to combat orthostatic hypotension in patients with autonomic dysfunction[J].Clin Auton Res,2004,14(3):167-175.
[11]Podoleanu C,Maggi R,Brignole M,et al.Lower limb and abdominal compression bandages prevent progressive orthostatic hypotension in elderly persons:a randomized single-blind controlled study[J].J Am Coll Cardiol,2006,48(7):1425-1432.
[12]Berthet K,Lukaszewicz AC,Bousser MG,et al.Lower body positive pressure application with an antigravity suit in acute carotid occlusion[J].Stroke Res Treat,2010.pii:950524.doi:10.4061/2010/950524.
[13]Lucas RA,Ainslie PN,Morrison SA,et al.Compression leggings modestly affect cardiovascular but not cerebrovascular responses to heat and orthostatic stress in young and older adults[J].Age(Dordr),2012,34(2):439-449.
[14]吴 斌,薛月英,由广兴,等.加速度致意识丧失前驱反应特征及预警方法研究[J].空军医学杂志,2011,27(1):28-32.

备注/Memo

备注/Memo:
收稿日期：2014-04-24.
基金项目：兰州军区“十二五”基金项目资助（CLZ13JA18）
通讯作者：孙喜庆，教授，主要从事重力生理学研究Email: sunxiqing@fmmu.edu.cn
作者简介：吕云利，主任医师Email：ljy85211@sina.com
更新日期/Last Update: 2015-01-20