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|本期目录/Table of Contents|

经皮冠状动脉介入治疗患者造影剂肾病的发病率及其相关因素

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

期数:
2015年第2期
页码:
142-144
栏目:
临床研究
出版日期:
2014-10-25

文章信息/Info

Title:
Morbidity and related factors of contrast-induced nephropathy in patients undergoing percutaneous coronary intervention
作者:
丁 琦; 欧阳茂
(中南大学湘雅三医院心内科，湖南 长沙 410013)
Author(s):
DING Qi;  OUYANG Mao
(Department of Cardiology, Third Xiangya Hospital, Central South University, Changsha 410013, Hunan, China)
关键词:
造影剂肾病; 危险因素; 水化治疗; 经皮冠状动脉介入
Keywords:
contrast-induced nephropathy;  risk factor;  hydration;  percutaneous coronary intervention
分类号:
R541.4
DOI:
-
文献标识码:
A
摘要:
目的:调查分析他汀类药物和充分水化治疗后经皮冠状动脉介入（PCI）治疗患者的造影剂肾病（CIN）发病率和可能的危险因素。方法:连续入选PCI治疗的冠心病患者，分析PCI前后肾功能指标的变化，计算CIN的发病率，比较CIN组和非CIN组的相关指标，寻找可能的危险因素。结果:①本组患者CIN发病率为13.8%；②多因素相关性分析发现高龄、内生肌酐清除率、贫血、高血压是CIN的危险因素。结论:PCI患者正规治疗后CIN发病率与文献报道CIN平均发病率相比无明显降低，高龄、内生肌酐清除率、贫血、高血压病是CIN的独立危险因素。
Abstract:
AIM:To investigate the morbidity and risk factors of contrast-induced nephropathy (CIN) in patients undergoing percutaneous coronary intervention (PCI) after conventional treatment, including risk assessment before PCI, optimal hydration before and after PCI and statin therapy. METHODS: One hundred and eighty-one consecutive patients who underwent hydration and PCI were enrolled. Serum creatinine was measured before and 72 h after PCI. RESULTS: The morbidity of CIN was 13.8%. Multiple logistic regression analyses showed that CIN was associated with pre-contrast creatinine clearance, old age, lower hematocrit value and hypertension. CONCLUSION: The morbidity of CIN after conventional treatment is not noticeably lower than the average incidence reported in the literature. Pre-contrast creatinine clearance, old age, anemia and hypertension are independent risk factors for CIN.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期：2014-04-20.
通讯作者：欧阳茂，副教授，主要从事冠心病的诊治研究 Email:doctorouyang@126.com.
作者简介：丁琦，硕士生 Email：dingqi.6648020@163.com
更新日期/Last Update: 2014-11-18