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Title:: Curative effect of metoprolol in prevention and treatment of atrial fibrillation after coronary artery bypass transplantation

作者:: 王振利; 张云涛; 郭立新; 夏晓君; 王艳玲; （邢台市第三医院、邢台市心血管病医院心外科，河北邢台 054000）

Author(s):: WANG Zhen-li; ZHANG Yun-tao; GUO Li-xin; XIA Xiao-jun; WANG Yan-ling; (Department of Surgery, Xingtai NO.3 Hospital & Xingtai Cardiovascular Hospital, Xingtai 054000, Hebei, China)

关键词:: 美托洛尔; 冠状动脉旁路移植术; 心房颤动

Keywords:: metoprolol; coronary artery bypass graft; atrial fibrillation

分类号:: R541.7

DOI:: -

文献标识码:: A

摘要:: 目的:观察和分析美托洛尔防治冠状动脉旁路移植术（CABG）后心房颤动的疗效。方法:将332例连续行CABG患者，依据术后使用美托洛尔的剂量和控制心室率水平分为美托洛尔足量组（足量组）和美托洛尔适量组（适量组）。足量组用足量美托洛尔控制心室率水平在70次/min以下。适量组：使用适量美托洛尔，心室率控制在85次/min以上。结果:足量组与适量组两组患者在年龄、体质量指数、移植的病变血管部位、心功能分级、左室射血分数、体外循环时间和气管插管时间等两组比较无显著性差异。适量组：发生房颤数54例，房颤发生率32.5%；足量组：房颤发生数21例，房颤发生率12.7%，足量组术后心房颤动的发生率显著低于适量组，两者比较有显著性差异（P<0.05）。结论:足量美托洛尔防治CABG后心房颤动安全、有效。

Abstract:: AIM:To investigate the curative effect of metoprolol in prevention and treatment of atrial fibrillation (AF) after coronary artery bypass graft (CABG). METHODS: We retrospectively analyzed the clinical data of 332 CABG patients in our hospital from January 2010 to January 2013. According to the postoperative ventricular rate, patients were divided into group A and group B, with 166 cases in each group. In Group A, the ventricular rate was controlled <70 times/min using adequate metoprolol and in Group B, the ventricular rate was controlled >85 times/min using suitable amount of metoprolol. RESULTS: No significant difference between groups was found in age, body mass index, ejection fraction, extracorporeal circulation time, and endotracheal intubation time (P>0.05). The incidence of AF in Group A was obviously lower than that in group B, with significant difference between groups (P<0.05). CONCLUSION: It is safe and effective to use metoprolol in prevention and treatment of AF after CABG.

参考文献/References

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足量美托洛尔防治冠状动脉旁路移植术后心房颤动的疗效

《心脏杂志》[ISSN:1009-7236/CN:61-1268/R]

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